Forecasting of the Traffic Situation in the Hannover Region

The main requirement of road traffic participants is to know the current traffic situation. Such data is typically obtained from routing services where the time of many different individual trips is taken into account.

In the context of Data4UrbanMobility tools were developed that allow to predict the traffic situation based on such time series data. The following figure presents an interface to visualize typical time series patterns as well as outliers present in the data:

The prediction of the traffic situation is made available in the form of a map based interface for the end user:

Data4UrbanMobility Data Protection Regulation

The work on the Data4UrbanMobility data protection regulation is completed. The document is publicly available and can be found here.

First Version of MiC-App Available

A first version of the novel MiC-App (Move in the City) App is now available for D4UM-associates as well as a protected group of public users. The mobile MiC-App is a tool to gather data.

MiC was developed by the Institute for Sustainable Urbanism at the University of Braunschweig and the Projektionisten GmbH. MiC links the growing  awareness of  digital citizen rights with the potential of evaluation big datasets. Therefore MiC gives the opportunity to citizen to actively participate in a citizen science project to take part in the development of the mobility of the feature.

MiC gathers data of the users movement, where the user has the about which data should be recorded. All data is pseudonymised such that the privacy of the contributing citizen is ensured.

Current Status:

In the first version of the app, the user can easily start and end the tracking of his/her movement. It is worth to point out, that the user decides when he is tracked and when not. A summary of his/her activity is available for the user as well as the opportunity to issue feedback or even delete all of his contributed data.

Updated System with Dashboard V2

With the new version of our system,  the dashboard will provide even more insights into the impact of public events on the traffic situation.

The coloring and labels let us easily distinguish between the different type of events. By clicking on the label we show the typically affected subgraph for that event type. This allows the user to check what specific routes are typically affected by an event at that location.

Examples: Visualisation of a concert and a football game.

In addition, the graph at the top right gives additional information on how big the impact around the events start time tends to be.

{API}
We enriched the api endpoints with additional information from the data models that were developed as part of the research efforts.

D4UM App Version 1.0

We just released the first Version of the D4UM App. Every project member now has access to the application and can try out its features. Let’s quickly go over some of its main features.
The EFA integration (EFA is a routing engine covering Lower Saxony and Bremen ) allows for quick access to tip information using all available public transport options. Our focus, when designing the application, was on quick and easy navigation to provide a simple and easy to use trip planning tool.

Departures and Connections

On the departure screen we show the user the closes stops for public transportation in his immediate vicinity. On the connection screen the user can fill in his desired starting location( either an address or an existing stop ) and destination and query for what connections are available to him. The provided information contains real time data , meaning we are able to visualized delays for any given connection.

Map

On the map screen you can see and or find all available stops of public transportation. This allows for providing the user with a great way to find out what stops are available in their city. By clicking on any of the shown stops will open the departure screen and provide you with the information mentioned above. To better visualize a selected connection, we show the route you plan to travel on the map.

Menu / Settings

Additional features can be found in the settings menu of the application. Here you can find settings that allow you to customize your routing results for both the departures and connection screen. The best way to let us know what you think about the application is to use the feedback module. This can be found here as well. First click on the emoji that best describe how you feel about the app. And then put in any additional information or ideas or thoughts you may have. Now what is left is just to press send and you will send us an email.

We look forward to hearing from you.

Quantification  and Prediction of Impact of Public Events

Current Data4UrbanMobility research results allow for measuring and prediction of spatial impact on road traffic of public events. Connected, affected street segments nearby public events are identified to measure the spatial impact. The approach is depicted in the following figure:

(Karte von https://www.openstreetmap.org)

An event is marked as yellow dot, affected streets in red and the measured impact in dark blue. Moreover, an approach making use of machine learning algorithms was developed to predict the impact determined in this way, resulting an error-reduction of up to 40% when compared to existing state-of-the-art approaches.

D4UM – Platform V1 Released

The first version of the Data4UrbanMobiltiy platform has been released. The platform was designed and implemented following a 3-tier-architecture. The platform provides RESTfull Web services for mobility applications like dashboards or mobile apps. As a demonstration, an interactive map application has been developed that visualizes the spatial impact of public events. The following figure shows a screenshot of the application.

The figure shows 4 public events in the city of Hannover. The colors represent different types of public events (e.g. concerts, fairs, sport events). The circles visualize the spatial impact on road traffic caused by the public events.

Comprehensive Set of Requirements

The Data4UrbanMobility analysis of requirements includes requirements of the application partners Region Hannover (RH) and Wolfsburg AG (WAG) as well as non functional requirements. The requirements were collected by MOMA. The L3S derived research question for data analysis which are based  on the requirements of RH and WAG. The research question address especially the information needs of end-users.

The current research questions particularly include

1. Automated verification of traffic warnings and prediction of their impact
2. Identification of events and prediction of their impact
3. Investigation of correlation of road traffic data, public transportation query logs, traffic warnings and twitterfeeds
4. Determination of optimal traveling timepoints

Growing Data Collection

ISU create a comprehensive data matrix containing potential source of mobility related data. The Data4UrbanMobility data model describes all project relevant data sets and sets them into context. This makes the data available in a unified manor for both analysis and applications. The selected data sources were transformed according to the Data4UrbanMobility data model by L3S. The data quality of selected data sources (i.e. public transportation query logs and road traffic data) was examined.

Tools for extracting the relevant information from the datasets were developed to enable the integration of the datasets.

• Street and graph extraction from OpenStreetMap
• Bulkloader for public transportation queries
• Integration of “Zentrales Haltestellen Verzeichniss” (central registry of public transportation stops)

The current collection (December 12th 2017) contians

EFA-Logs: 17 million public transportation queries
Road traffic data: 174 thousand street sements with a frequency of 15 minutes
GTFS-data: 90 thousand. public transportation stops, 2.6 thousand routes
Weather: Radolan “Regenraster” (rain grid)
Twitter: 2,5 Mio. Tweets starting at June 2017

OSM: 440 thousand streets 
Events: 21 thousand public events (August 14th 2016-July 17th 2018)

Traffic warnings: 13 thousand warning (since June 2017)

Visualization of Public Transportation Information

In order to allow intuitive analytics of public transportation information, the PROJEKTIONISTEN (PROJ) developed a dashboard web application. First prototypes visualize queries addressed to the regional timetable information system EFA (www.efa.de). The prototypes serve as foundations for exploration analyses as well as the implementation of future versions of the dashboard. The following figure shows an integrated visualization of the most frequent origins and destinations of the queries.

Analysen der EFA-Logs

Analysis of EFA Public Transportation Query Logs

Analyses regarding the impact of public events on public transportation are currently conducted to address early research questions. To this extend, explorative data analyses of the impact of major public events such as football games and medium sized events such as concerts were conducted. Visual analytics were used as a first step towards comprehensive analyses, which show start-like patterns for city center which identify mobility hubs of central importance.

The figure shows the direct connection between origin and destination of public transportation queries. Darker colors correspond to more frequent queried trips. Star-like pattern identify the central train station and the central metro station.

Analyses of single stations reveal weekday dependent patterns.

The figure depicts the average number of queries with the destination “Hannover Stadionbrücke”. Differences emerge between Weekends and workdays.

The impact of public events on the queries can be visualized  as well.

The figure shows the number of queries with the Destination “Hannover Stadionbrücke” for Wednesday, April 26th 2017 (orange) as well as the average number of queries on a Wednesday for the same destination. On this day a concert took place in venue nearby. The concert start at 8 pm. The significant deviations between 5 pm and 7 pm is highly likely to be caused by visitors of the concert. This shows that public transportation queries are a valuable information source to investigate the impact of public events on mobility infrastructure.

• Making AI Reporting Actionable: A Taxonomy for Future Information Systems Research. van der Staay, Alexander; Fischer, Raphael; Geist, Roman; Markic, Mihael; Janiesch, Christian (2027).
• PCAP-AIDE: AN EXPORTER-FREE HYBRID NIDS WITH AUTOMATED FLOW-LEVEL FEATURE ENGINEERING AND SHAP-GUIDED FALSE POSITIVE REDUCTION. Cho, Sung-Jun (2026). 18(4) 75–96.

  Modern enterprise networks face an escalating volume of sophisticated cyber-attacks that traditional signature-based network intrusion detection systems (NIDS) fail to counter. Existing machine learning (ML)-based NIDS (ML-NIDS) exhibit three fundamental operational limitations: (i) dependency on proprietary flow exporters that create vendor lock-in and restrict privacy-sensitive deployments; (ii) susceptibility to class imbalance that degrades generalization across heterogeneous attack categories; and (iii) opaque decision processes that erode operational trust and hinder alert triage. These gaps collectively prevent ML-NIDS from achieving reliable, reproducible, and explainable detection in real-world deployments. This paper presents a new packet capture artificial intelligence detection engine (PCAPAIDE), an open-source hybrid NIDS that addresses all three limitations through four coordinated contributions: (C1) a self-contained 35-dimensional flow feature extractor operating directly on raw PCAP or standard CSV records, eliminating exporter dependency; (C2) stratified reservoir sampling with a class of weight-balanced random forest (RF) classifier, providing imbalance-resilient training on datasets exceeding 2.5 million flows; (C3) FlowFPFilter v3.0, a SHAP-guided post-processing filter that reduces false positives by 22.9% while preserving recall; and (C4) a five-protocol robustness evaluation framework that rules out data-leakage artefacts and confirms statistical stability across algorithm variants and random seeds. Evaluated on CIC-IDS2018 and the complete four-part UNSW-NB15 dataset (2.54 M flows; nine attack categories), PCAP-AIDE achieves F1 = 0.9997 and F1 = 0.9919, respectively, surpassing the AdvIDS-2025 baseline by ΔF1 = +0.0729 and +0.0479. FPR on UNSW-NB15 is 0.0144 — within the operational acceptance threshold of <2%. Ten-seed variance analysis confirms F1 standard deviations of 0.0001 (CIC) and 0.0005 (UNSW). PCAP-AIDE is released as a fully open-source pipeline, providing a deployment-ready, interpretable, and statistically validated solution for modern network security.
• Dynamic coupling of cell fate specification and cell sorting during mouse preimplantation development. Ollertz, Sascha; Muñoz-Descalzo, Silvia; Fischer, Sabine C. (2026).

  During preimplantation development in mice, cells of the inner cell mass undergo a cell fate decision to become either Epiblast (Epi) or Primitive Endoderm (PrE) cells. Cell fate patterns during this stage range from an alternating pattern at the beginning to the separation of Epi and PrE at the end. Several mechanisms guiding this decision and pattern formation have been proposed, including intra- and intercellular signalling, cell division and cell sorting. The current understanding is that signalling generates the cell fates and subsequent sorting introduces the spatial cell fate separation. We used agent-based modelling to investigate whether cell differentiation and cell sorting can act concurrently and how their relative contributions to pattern formation may change over time. Comparing our model to experimental data for mouse blastocysts and ICM organoids, we find two mechanistic regimes that can produce the experimentally observed spatial separation: (i) simultaneous long-range intercellular signalling and cell sorting, and (ii) a gradual transition from short-range signalling to cell sorting, in which the timing is mediated via reducing cell fate plasticity. While the second agrees better with existing experimental evidence for late blastocysts, the first might still be relevant for early and mid blastocysts. Together, our results refine the sequential view of Epi/PrE patterning by showing that fate specification and cell sorting can be dynamically coupled, with their relative contributions changing over the course of blastocyst development.Competing Interest StatementThe authors have declared no competing interest.Deutsche Forschungsgemeinschaft (DFG, German Research Foundation), 470129398
• BUSINESS RULE MANAGEMENT FRAMEWORK FOR ENTERPRISE WEB SERVICES. M1, Thirumaran; E2, Ilavarasan; K3, Thanigaivel; S4, Abarna (2026, December).

  This workbook on European Works Councils (EWCs) is designed as a training tool for people with some experience with EWCs, so it does not include the basics of the EWC such as the Directive or a checklist for agreements. It is also aimed at trainers and coordinators of EWCs, so outlines of training activities are included throughout the text. These are not comprehensive activity sheets. Trainers will need to adjust the material to the specific kind of training course: international or national, for one EWC or for reps from different EWCs, etc.
• Mind The Margins: Probing Link Prediction via Perturbations. Memariani, Adel; Sharma, Arnab; Röder, Michael; Ngonga Ngomo, Axel-Cyrille in Lecture Notes in Computer Science (2026).
• Ergosterol-depleted clinical isolates of <i>Nakaseomyces glabratus</i> can develop multi-drug resistance without severe fitness defects or attenuated virulence in an invertebrate infection model. Aldejohann, Alexander M.; Thielemann, Nadja; Zurita, Aina Martinez; Müller, Christoph; Gräfenhan, Tom; Kriz, Richard; Lagler, Heimo; Behr, Isabell S.; Reus, Nathalie; Schöninger, Annika; Walther, Grit; Mazan, Lena-Marie; Wilhelm, Hannah; Willinger, Birgit; Cuomo, Christina A.; Kurzai, Oliver; Martin, Ronny (2026). 17(6) e02731–25.

  ABSTRACT Nakaseomyces glabratus (formerly Candida glabrata) is a leading cause of invasive candidiasis and rapidly develops antifungal drug resistance during treatment. An increasing number of clinical isolates show reduced susceptibility to echinocandins and azoles, leaving amphotericin B (AMB) as a last therapeutic option. Resistance of N. glabratus to this drug is rare, and its underlying mechanisms are still not fully understood. Here, we describe two independent multidrug-resistant bloodstream isolates displaying resistance to AMB and anidulafungin (ANF), as well as a reduced susceptibility to azoles. We performed whole-genome sequencing and sterol profiling on nine clinical N. glabratus isolates, which were resistant to ANF and displayed resistance or low susceptibility to fluconazole (FLU) and AMB. We identified loss-of-function mutations in the genes ERG3 and ERG4, which could be linked to ergosterol depletion and AMB resistance. The transcriptional response of the reference strain CBS138 and an AMBR + ANFR isolate was analyzed by RNA-seq, revealing that ergosterol depletion also contributed to upregulation of ERG and ABC transporter genes, which might explain the low FLU susceptibility. Surprisingly, the AMBR isolates displayed severe fitness defects, and one of them was fully virulent in a Galleria mellonella infection model. Our results indicate that ergosterol depletion in N. glabratus leads to AMB resistance without affecting fitness or virulence.IMPORTANCE The major human fungal pathogen Nakaseomyces glabratus is well known for its fast development of antifungal drug resistance, especially against commonly used azoles. However, it can also acquire resistance to echinocandins, leading to multidrug resistance (MDR) and leaving amphotericin B (AMB) as the last therapeutic option. AMB resistance is rare, mainly caused by ergosterol depletion, and is normally associated with severe fitness costs for the pathogen. However, we found N. glabratus bloodstream isolates with stable AMB resistance without apparent fitness and virulence defects. The underlying ergosterol depletion contributed to low azole susceptibility and was associated with anidulafungin resistance. These findings demonstrate how fast MDR can evolve in N. glabratus and underline the need for close resistance monitoring.
• Low-dose allergen targeting to cDC2 induces long-term protection associated with induction of regulatory-like IL-10+ Foxp3- CD8+ T cells in mice. Aintablian, Arpa; Cyran, Laura; Helal, Moutaz; Lehmann, Christian H.K.; Imdahl, Fabian; Gräfenhan, Tom; Riedel, Angela; Dudziak, Diana; Kerstan, Andreas; Lutz, Manfred B. (2026). Volume 17 - 2026

  The prevalence of allergic diseases is rising worldwide. Desensitizing immunotherapy is currently the only available treatment, but it is often ineffective for certain allergies, underscoring the need for new treatments. This study tested in an Ovalbumin (OVA)-mediated allergy mouse model whether direct allergen targeting to DC subsets can induce desensitization. A Standard desensitization protocol was compared with an antibody-OVA fusion protein targeting the conventional cDC1 or cDC2 subsets via their respective receptors CD205 (CD205-Fp) or DCIR2 (DCIR2-Fp). Allergen targeting to cDC2 provided long-lasting protection for up to 56 days after desensitization with only nanogram doses of allergen, whereas the Standard therapy protected for only 20 days, requiring microgram doses and repeated injections with Alum adjuvant. CD205-Fp showed no protective effect. Blocking IL-10 either before administering DCIR2-Fp or before allergen challenge completely abolished protection. Standard therapy had moderate effects on CD4+ T cells, with early expansion of IL-10+ Foxp3- T regulatory type-1 cells (Tr1), followed by an increase in both IL-10+ and IL-10- Foxp3+ regulatory T cells (Foxp3+ Treg). DCIR2-Fp therapy initially expanded IL-10+ and IL-10- Foxp3+ Treg, but these levels returned to baseline. On day 80, we identified Foxp3- CD44high Treg-like CD8+ as the primary source of IL-10. Overall, our data suggest that cDC2 allergen targeting in allergic mice offers a potent, long-lasting IL-10-dependent desensitizing effect.
• A sense of purpose: Building resilient communities with civic action. McCauley, Maria (2026). 57(September 1)

  When it comes to building resilient and equitable communities, libraries are natural leaders. We provide places where neighbors meet, learn, and support one another; where sustainability education becomes action; and where residents can find year-round climate refuge. When communities are resilient, they are better able to overcome barriers.
• Guiding youth from eco-anxiety to empowerment: Climate action programming for school and public libraries LaPort, Kelsey; Reich, Noel (2026). ALA Editions.

  ith an emphasis on nurturing curiosity, action, and community-building, this book's rich assortment of sustainability- and climate justice-centered programs helps school and public librarians and educators move beyond simply providing information to becoming catalysts for empowerment---supporting young people as they cope, connect, and take meaningful climate action. Sustainability, one of the Core Values of Librarianship, is spurring libraries to lead the way in guiding their communities towards climate action. However, because people's lives are affected every day by the increasing frequency and intensity of natural disasters, engaging with the impacts of climate change can be an isolating and difficult experience for adults and youth alike. This hands-on guide offers a solution to cool down eco-anxiety by transforming it into a force for engagement and hope. Through programming that centers agency and belonging, librarians and educators can reframe the negative impacts of eco-anxiety into positive goals designed to inspire young people towards climate action. Presenting 60 research-based ideas and supporting resources designed to promote collaboration and partnership, the authors walk readers through concrete, adaptable steps to impactfully integrate climate action into programming regardless of a library's size or budget. This book grounds its approach in the ``triple bottom line'' framework of sustainability used by ALA and the Sustainable Libraries Initiative (SLI) while also aligning with the six Shared Foundations of the AASL Standards; directly addresses the emotional realities of eco-anxiety such as apathy, fear, and isolation by offering strategies that foster connection and resilience; shows librarians and educators how to help K-12 learners develop the mindset, skills, and knowledge required to become climate-actionable; provides primary and secondary school library lessons, children and young adult public library programs, and collaborative programs for all ages that are geared towards curiosity, agency, community, and real-world impact; and includes book lists, information about activists and organizations, and links to additional resources.
• Detection and Exploration of References between Scholarly Texts and Literary Works. Technical Report (PhD dissertation), Arnold, Frederik (2026).
• Das große Krabbeln in der Bibliothek. Bunge, Eva (2026).

  Zusammenfassung: Wir alle mussten uns wohl schon einmal mit ihnen auseinandersetzen, auch wenn die wenigsten von uns gerne darüber sprechen: Mehlwürmer, Kleidermotten, Ameisen, Mäuse, Silber- und Papierfischchen, Schaben, Teppichkäfer und ähnliches Getier, das in der Wohnung umherkreucht und fleucht. Zusammengefasst werden diese Tiere oft als Schädlinge bezeichnet. Denn auch wenn sie biologisch betrachtet durchaus wichtige Funktionen wahrnehmen, so richten sie in und an menschlichen Behausungen doch oft beträchtlichen Schaden an. Kultureinrichtungen wie Archive, Bibliotheken und Museen sind von dieser Gefahr nicht ausgenommen und haben aufgrund des in ihnen bewahrten, oft einzigartigen Kulturguts eine besondere Sorgfaltspflicht auch hinsichtlich der Schädlingsbekämpfung. Dieser Beitrag soll anhand einer kleinen Wanderausstellung, die von Januar bis April 2026 am Deutschen Museum in München Station machte, einen Überblick über Hintergründe, Methoden und aktuelle Entwicklungen der sogenannten glqqIntegrierten Schädlingsbekämpfunggrqq (oft wird auch im Deutschen der englische Fachbegriff IPM für \glqqIntegrated Pest Management\grqq verwendet) geben. Abstract: Most of us have likely had to deal with them at some point, even if few of us enjoy talking about it: mealworms, clothes moths, ants, mice, silverfish and paperfish, cockroaches, carpet beetles, and similar critters crawling and scurrying around the home. Collectively, these creatures are often referred to as pests. Although they perform vital biological functions in nature, they often cause considerable damage within and to human dwellings. Cultural institutions such as archives, libraries, and museums are not exempt from this threat and, due to the often unique cultural heritage they preserve, bear a special responsibility regarding pest control. Based on a small traveling exhibition that was hosted at the Deutsches Museum in Munich from January to April 2026, this article provides an overview of the background, methods, and current developments in the so called glqqIntegrierte Schädlingsbekämpfunggrqq (often referred to by the English term IPM for \glqqIntegrated Pest Management\grqq, even in German).
• Reproducibility of Experiments in Networking. Wehner, Nikolas; Grigorjew, Alexej; Raffeck, Simon; Goedicke, Michael; Hoßfeld, Tobias (2026).

  Reproducibility is a cornerstone of good scientific practice, enabling validation of experimental results and fostering progress by building upon prior work. The importance of reproducibility in networking research has gained traction in recent years. Notably, the Dagstuhl beginner’s guide to reproducible experimental networking research has provided valuable best practices for documentation, data handling, and experiment design. However, the identification of specific networking components and aspects that prevent experiment reproducibility has not been investigated yet. This work addresses this gap by systematically identifying such components, constructing a taxonomy based on the findings, and proposing guidelines to increase experiment reproducibility. For this purpose, we discuss and analyze several networking use cases: 5G measurement experiments, Internet measurements, AI/ML-based networking experiments, and subjective QoE studies. Through targeted experiments and a review of existing studies, we identify some key sources of variability and discuss strategies to reduce variability and thus increase reproducibility. Our analysis highlights the importance of clearly defining research questions and expected outcomes as they form the foundation for assessing reproducibility. Additionally, our findings show the need for documenting potential sources of randomness, e.g., platform-specific effects introduced by operating systems, prior to experimental design. Minimizing unnecessary variability, e.g., by abstracting or replacing such components, further enhances reproducibility. While not all variability can be controlled due to the inherent complexity of networked systems, the proposed guidelines offer practical steps toward more reproducible networking experiments.
• Taxonomy and Literature Review Description for "Making AI Reporting Actionable". van der Staay, Alexander; Fischer, Raphael; Markic, Mihael; Geist, Roman; Janiesch, Christian (2026).
• How can remote sensing support urban tree cadaster efforts and diversity analysis of dominant genera?. García de León, Andrea Sofía; Leichtle, Tobias; Droin, Ariane; Rieder, Julia; Castaneda-Gomez, Antonio Jose; Rotzer, Thomas; Martin, Klaus; Ullmann, Tobias; Taubenbock, Hannes (2026). 1–17.
• Die Rolle von Bibliotheken der Dinge bei der Förderung nachhaltiger Konsumpraktiken: Eine empirische Untersuchung. Bachelorarbeit. Technical Report (PhD dissertation), Heim, Carolin Ramona (2026).

  Diese Veröffentlichung geht zurück auf eine Bachelorarbeit im Studiengang Bibliotheks- und Informationswissenschaft (Library and Information Science), B. A. an der Humboldt-Universität zu Berlin aus dem Jahr 2026. Nachhaltiger Konsum gewinnt vor dem Hintergrund ökologischer Krisen, Ressourcenknappheit und sozialer Folgen übermäßigen Konsums zunehmend an Bedeutung. Vor diesem Hintergrund stellt sich die Frage, wie öffentliche Institutionen zu nachhaltigeren Konsumpraktiken beitragen können. Öffentliche Bibliotheken erweitern ihr Aufgabenspektrum über die Bereitstellung von Medien hinaus und verleihen zunehmend auch Alltagsgegenstände. Die Einzelfallstudie untersucht die Bibliothek der Dinge (BdD) der Humboldt-Bibliothek im Berliner Bezirk Reinickendorf aus Sicht der Nutzenden und leitenden bibliothekarischen Fachkräfte. Leitfadengestützte Interviews beleuchten Nutzungsmuster, -motivationen sowie Gründungsmotivation und Umsetzung im Hinblick auf Nachhaltigkeitsaspekte. Darauf aufbauend wird ein Ursache-Wirkungs-Modell nachhaltigen Konsums am Beispiel der BdD abgeleitet, das zeigt, dass nachhaltiger Konsum in der BdD von der Umsetzung, unter anderem durch gezielte Produktwahl und die Erweiterung des Nutzerkreises sowie von Unterstützung durch Personal und finanzielle Mittel abhängt. Die Untersuchung unterstreicht damit die zentrale Rolle öffentlicher Bibliotheken als relevante Akteure sozial-ökologischer Transformationen.
• Von Bibliotheken der Dinge zu Zentren des Teilens: Werkstattbericht aus einem Verbundforschungsprojekt. 114. BiblioCon, Berlin. Kleinod-Freudenberg, Michael; Krohn, Annette (2026).

  Die Neuerfindung der Bibliotheken in Zeiten der Digitalisierung ist Herausforderung und Chance zugleich. Während der gleichberechtigte Zugang zu physisch versammelten klassischen Medien an Bedeutung verliert, wird die traditionelle Funktion der Bibliothek als Ort des Teilens zu einem wichtigen Baustein kommunaler Kreislaufwirtschaft -- Stichwort: Bibliotheken der Dinge. Bisher konzentrieren sich lokale Initiativen zur Kreislaufwirtschaft meist auf Abfallwirtschaft und End-of-Pipe-Prozesse. Ding- und Werkzeugbibliotheken dagegen setzen bereits beim Konsum an. Durch gemeinschaftliches Nutzen statt individuellem Besitz fördern sie Ressourceneffizienz sowie nachhaltige Konsumgewohnheiten und -strukturen und fungieren zudem als glqqDritte Ortegrqq, in denen soziales Miteinander gestärkt wird. Empirische Daten zu ihrem ökologischen und sozialen Potenzial liegen bisher jedoch nur sehr spärlich vor. Im Rahmen von Circular Economies -- Circular Cities.NRW (gefördert von der EU und dem Land Nordrhein-Westfalen) untersucht das Projekt glqqZentren des Teilensgrqq, wie das gemeinschaftliche Nutzen von Gebrauchsgütern durch Designforschung erweitert und institutionalisiert werden kann. Beteiligt sind die Stadt Essen, die Fachhochschule Dortmund und Fraunhofer UMSICHT in Oberhausen. Auf Grundlage langjähriger Erfahrungen mit der glqqBibliothek der Dingegrqq an der Stadtbibliothek Essen werden mithilfe partizipativer Methoden noch weitreichendere Formen des Teilens erprobt. Ziel ist die Entwicklung und das Testen von Prototypen für Zentren des Teilens -- d.h. Nachbarschaftseinrichtungen, die sich dem Teilen, Wiederverwenden und Reparieren von Alltagsgegenständen in größerem Umfang als bisher widmen. Hierfür werden auch digitale Lösungen wie Leih-Apps und Sharing-Plattformen getestet. Der Vortrag stellt Hintergrund, Struktur und Ziele des Projekts vor und präsentiert erste Ergebnisse aus quantitativer und qualitativer Forschung.
• Advancing sustainable development through public libraries: An Indian knowledge system approach. Jena, Biswo Ranjan (2026). 3(1) 17–29.

  This research aims to explore how public libraries across India contribute to sustaining development through the Integration of the Indian Knowledge System (IKS) into the services, activities and community engagement of their members. The focus of this research is on understanding how successfully libraries have been in providing sustainable education, and raising environmental, cultural and heritage awareness and preservation through supporting Sustainable Development Goals (SDGs). The research used a qualitative methodology to examine library and policy records of libraries across India, and other literature pertinent to IKS and libraries. The results of the data collected indicate that many libraries throughout India have initiated programs that are focused on the preservation of cultural traditions, traditional crafts, the awareness of cultural and historical heritage, and, more specifically, environmental education utilizing locally Indigenous knowledge. These initiatives are important because they provide a mechanism for communities to reconnect with their heritage and develop the skills and understanding necessary for a more sustainable lifestyle. The strength of the connection made between traditional wisdom and modern-day needs of the community, through IKS by libraries, creates a system of Local Indigenous Knowledge that facilitates the learning journey for communities, Cultural Awareness and Environmental Responsibility.Keywords: Public Libraries, Sustainable Development Goals (SDGs), Indian Knowledge System (IKS).
• Establishing a Functional use for the Middle Stone Age (MSA) Engraved Blombos Ochre Stone through Image-based Vectorization, Use-Wear Constraints, and Experimental Reconstruction. Stein, Silvia (2026). 13(2) 01–08.
• Tổng quan nghiên cứu về khởi nghiệp bạc và khoảng trống nghiên cứu tại Việt Nam. Thị Nam Thắng, Trương (2026). 712(2) 69–74.

  Khởi nghiệp bạc, hoạt động kinh doanh của người từ 50 tuổi trở lên, đang nổi lên như một lĩnh vực nghiên cứu quan trọng trong bối cảnh già hóa dân số toàn cầu. Bài viết thực hiện tổng quan tài liệu có hệ thống nhằm (i) Trình bày sự hình thành khái niệm, các cách tiếp cận lý thuyết, mô hình và phát hiện chính từ nghiên cứu trên thế giới; (ii) Đánh giá hiện trạng nghiên cứu tại Việt Nam; và (iii) Xác định các khoảng trống nghiên cứu cần lấp đầy. Kết quả cho thấy, dòng nghiên cứu quốc tế đang phát triển mạnh, chủ yếu từ các nước phát triển, tập trung vào động lực khởi nghiệp, rào cản nguồn lực và tác động chính sách. Tại Việt Nam, nghiên cứu học thuật về chủ đề này còn rất hạn chế và có khoảng trống nghiên cứu đáng kể. Bài viết đề xuất hướng nghiên cứu và khuyến nghị chính sách phù hợp với bối cảnh Việt Nam.
• Der Kulturkampf erreicht den Trinkwasserbrunnen. Yendell, Alexander (2026, September).

  Trinkwasserbrunnen, begrünte Fassaden und weniger Asphalt sollen Menschen vor Hitze und anderen Folgen des Klimawandels schützen. Eigentlich könnte man erwarten, dass solche konkreten Maßnahmen weniger polarisieren als Wärmepumpe oder Verbrenner-Aus. Doch neue Daten der STEADY-Studie zeigen deutliche politische Unterschiede: Unter AfD-Wählerinnen und ‑Wählern ist die Zustimmung zu Klimaanpassungsmaßnahmen besonders gering. Zur CDU/CSU-Wählerschaft beträgt der Abstand bei einzelnen Maßnahmen fast 30 Prozentpunkte.
• Mountain pine time series mapping with Sentinel-2 and assessing their ecological role in Alpine vegetation dynamics. Tufail, Basil; Rösch, Moritz; Rauth, Elio; Fäth, Julian; Ullmann, Tobias (2026). 43(102238)

  Mountain pine (Pinus mugo) is a critical species in the krummholz zone of alpine ecosystems and vital to understanding treeline dynamics under ongoing climate change. Despite their various ecosystem functions, their spatial distribution remains poorly quantified across complex mountain terrain. In this study, Sentinel-2 multi-temporal optical imagery, along with topographic and textural features, is used to train a random forest model and map the species in southern Germany at 10-meter resolution. The classification achieves an F1 score of 87.5–90.4% under spatially independent validation, and was applied to generate annual mountain pine distribution maps from 2017 to 2025. Applying the approach to higher-resolution UAS data acquired near Zugspitze in Summer 2025 highlights the sensor-scale limitation. This is evidenced by underdetection in the Sentinel-2 maps at higher elevations, particularly in landscapes with smaller, fragmented patches, due to mixed pixels at the Sentinel-2 scale. The annual mountain pine time-series maps highlight patch dynamics, distribution in relation to terrain, and a detectable upslope shift in the upper boundary of the distribution within the German part of the European Alps. To demonstrate the ecological relevance of these maps, an exploratory fixed-effects analysis suggests that greenness is influenced mainly by growing-season and early-winter temperature, pointing to an energy-limited system favoured by warming conditions. Our results highlight the potential of high-resolution species-level mapping using machine learning in data-limited regions. The approach provides scalable workflows for other species in alpine ecosystems, supporting robust monitoring amid ongoing environmental change.
• The Nuremberg Chronicle 1493: On the creation from nothing / On the mathematical point and the tetrahedron Schrausser, Dietmar Gerald (2026).

  The concept of the creation from nothing (creatio ex nihilo) implies, from the perspective of existing empiricism, strictly speaking, the assumption of a virtual structure of the existing empiricism, which is causally underlyed by an intangible, yet knowingly and willfully acting and creating real world, as also indicated in the Phænomena of Aratus. The basic assumption of a virtual structure of empiricism is also all too clear in the explanations of the orders of magnitude in Ptolemy’s Almagest: ” […] the earth has […] the ratio of a point to the distance of […] the fixed stars […]“. 
• Butterflies with low thermoregulatory capacity show greatest upwards range shifts along an elevational gradient. Ashe-Jepson, Esme (2026). 9(1) 1002.

  Climate change is a growing threat to global biodiversity, and so there is a pressing need to understand which traits impact species vulnerability, and the capacity of these traits to respond to environmental change. I quantify two thermal traits (thermoregulation, thermal tolerance) and functional traits (wing length, colouration, wing condition, sex) of butterflies across an elevational gradient in central Europe to investigate adaptation to local climatic conditions. There is no evidence of intraspecific variation in thermal traits, suggesting that these may be fixed within species. At low elevations, large species are better than small species at avoiding high body temperatures. Dark species have improved thermoregulatory capacities with decreasing elevation but ultimately have consistently higher body temperatures than pale species. This implies that small and dark species may be particularly vulnerable to extreme heat. I subsequently detect shifts from small dark species at high elevations to large pale species at low elevations. Finally, species with poor thermoregulatory capacity or larger wings have shown greater upwards elevational range shifts. This argues that butterflies are responding to climate change through redistribution of species rather than adaptation in place, and that thermoregulatory performance will be a key driver of ecological responses to climate change.
• Die Pension über Aktien zu finanzieren ist nicht nur riskant. Sie macht die Finanzmärkte mächtiger. Dobusch, Leonhard (2026).

  Der Ruf nach mehr privaten Pensionen ist nicht totzukriegen. Jetzt will Deutschland ihm nachgeben. Der Aktienmarkt boomt, also soll er die Renten finanzieren. So lautet das Versprechen, das die Finanz-Lobby herumposaunt. Aber private Pensionen bedeuten nicht nur mehr Risiko für Pensionist:innen - sie ändern das ganze Wirtschaftssystem. Sie treiben einen Keil zwischen Pensionist:innen und Beschäftigte.
• Experimental stopping power estimation in a homogeneous phantom via prompt gamma timing towards proton therapy monitoring. Werner, Julius; Pennazio, Francesco; Cerello, Piergiorgio; Fiorina, Elisa; Giordanengo, Simona; Milian, Felix Mas; Mereghetti, Alessio; Mostardi, Franco; Pullia, Marco; Ranjbar, Sahar; Sacchi, Roberto; Vignati, Anna; Rafecas, Magdalena; Ferrero, Veronica (2026).

  The full potential of proton therapy is limited by uncertainties that prevent optimal dose distribution. Monitoring techniques can reduce these uncertainties and enable adaptive treatment planning. Spatiotemporal Emission Reconstruction from Prompt-Gamma Timing (SER-PGT) is a promising method that provides insights into both particle range and stopping power, the calculation of which normally requires knowledge about patient tissue properties that cannot be directly measured. We present the first experimental proof of principle obtained using a 226.9 MeV synchrotron-proton beam impinging on a homogeneous phantom at a subclinical intensity (2 - \\($\$\)4 backslashtimes 10^7\\($\$\) pps). SER-PGT uses data from a multidetector setup: a thin and segmented Low Gain Avalanche Diode for proton detection and Lanthanum Bromide-based crystals for photon detection. The estimated stopping power profile showed an 8%textpm 3% average error compared with the NIST PSTAR values, and a 2%textpm 2% deviation relative to water at 100 MeV. Range assessment in a phantom with a 4 cm air gap successfully identified the range shift with a 3 mm standard deviation. For this proof-of-principle irradiation scenario, the experimental results demonstrate the recovery of both range and stopping power information through SER-PGT, particle kinematics and PGT measurements in a homogeneous target.
• When Confidence Turns Against You: Exploiting Link Prediction Scores for Data Poisoning. Memariani, Adel; Sharma, Arnab; Röder, Michael; Ngonga Ngomo, Axel-Cyrille in Lecture Notes in Computer Science (2026).
• Office, aber souverän! Wie digitale Arbeitsplätze ohne US-Abhängigkeiten funktionieren. Bleich, Holger; Friedrich, Greta (2026). (19) 16–23.

  Ein Leben ohne Microsoft 365 oder Google Workspace? Was nach digitaler Askese klingt, ist längst eine realistische Option. Europäische Anbieter kombinieren quelloffene Office-Komponenten zu eigenen Online-Arbeitsplätzen. Wir zeigen, was sie mit digitaler Souveränität zu tun haben und wo die Alternativen noch hinter den traditionellen US-Anbietern zurückbleiben.
• Pneumatically assisted gerotor pump system for high-volume bioprinting of viscous hydrogels. Behrends, André; Wendt, Dennis; Evers, Lea; Buzug, Thorsten (2026). (Vol. 8) 2766.
• Öffentliche Bibliotheken und Community Resilience - Was können sie zur Resilienz von Städten und Gemeinden leisten? 114. BiblioCon, Berlin. Schumann, Tim (2026).

  Der Vortrag untersucht, wie öffentliche Bibliotheken zur Stärkung urbaner Resilienz beitragen können. Ausgangspunkt ist der globale Transformationsdruck durch die VUCA-Welt und die Herausforderungen einer glqq2-Grad-Plus-Weltgrqq, die grundlegende ökologische, soziale und ökonomische Veränderungen mit sich bringt. Öffentliche Bibliotheken rücken dabei als besondere soziale Infrastrukturen in den Fokus: Sie sind konsumfreie, niedrigschwellige, für alle zugängliche Räume, die viele Menschen erreichen und in Städten häufig zu den meistbesuchten Bildungs- und Kulturorten gehören. Durch ihre lokale Verankerung in Nachbarschaften und ihre Funktion als glqqlow-intensive meeting placesgrqq besitzen sie ein hohes Potenzial, Gemeinschaften bzw. Communities zu stärken. Zentrales Konzept ist die glqqCommunity Resiliencegrqq -- eine entscheidende Säule urbaner Resilienz, die durch öffentliche Infrastrukturen gefördert wird. Der Vortrag zeigt, dass Bibliotheken in Deutschland diese Rolle bislang wenig reflektiert haben, während andere Länder bereits weitergehende Modelle bzw. Aktivitäten entwickelt haben. Durch internationale Beispiele soll ein vertieftes Verständnis dieses Tätigkeitsfeldes ermöglicht werden. Um Theorie und Praxis zu verbinden, dient die Stadtbibliothek Berlin-Pankow als Fallstudie. Auf Grundlage ihrer Leitbilder, Strategien und Konzepte wird ein praxisnaher Strategieentwurf entwickelt, der lokal wirksam ist und zugleich Ansatzpunkte für andere Bibliothekssysteme bietet. Der Vortrag basiert auf der Masterarbeit des Verfassers, die im Frühjahr 2026 eingereicht wird.
• Wann kommen Robotaxis nach Deutschland? Rechtsrahmen, Genehmigungsverfahren und aktueller Stand autonomer Fahrdienste. Dr. Baran Kizilirmak, LL.M. (L. Dr. Baran Kizilirmak, ed.) (2026).
• A data quality checklist for undergraduate data stewardship: Development, implementation, and evidence from two library courses. Zakharov, Wei (2026).
• PET-Physics: A Packing Evaluation Tool Considering Physics. Enzenhofer, F.; Ondrej, J.; Nüchter, A. (2026). 1–6.

  Without having a robotic bin packing setup, the prediction whether a packing plan results in a stable pallet is based on an informed guess based on prior experience. Since such a setup is costly, for many algorithms it is unclear if they are suitable for production. To close this gap, we provide our simulation framework PET-Physics that enables researchers to assess a solver’s quality. Based on the pose recording of all bodies, it is possible to check not only for static stability, but also dynamic stability of a packing plan. A novel feature of our tool is the provision of data that supports the detection of boxes that might be overloaded. We demonstrated the realism of our framework by comparing simulation runs with real-world palletization. Our packing evaluation tool considering physics is publicly available at https://github. com/floriankagerer/pet-physics
• Vestibular Physiotherapy Edmonton. point Physiotherapy, Turning (2026).
• Neue Federn: Wie Behörden sich aus der Abhängigkeit von Microsoft befreien. Wölbert, Christian (2026). (19) 24–27.

  Schleswig-Holstein war nur der Anfang: Immer mehr Behörden führen freie Office-Software ein, von kleinen Kommunen bis zu ganzen Landesverwaltungen. Das liegt nicht nur an Trump.
• AI-Augmented Human Resource Management? Insights from German companies. Kalff, Yannick; Simbeck, Katharina (2026, July 20).

  This study examines the integration of AI into Human Resource Management in German companies. We ask if and how AI-based technologies are ‘augmenting’ human resource management. Organisations employ generative AI or predictive analytics to transform traditional human resource functions, to streamline routine tasks and to reallocate resources toward strategic, people-centred activities. Our findings from interviews and group discussions and a survey (N=410) reveal that while AI tools enhance HR analytics capabilities, their adoption mainly serves efficiency and rationalising goals. The introduction of AI tools is shaped by organisational transformation factors such as digital infrastructure, co-determination frameworks, and ethical implications. The research highlights both the strategic potential for improved talent development and the challenges posed by data governance and algorithmic transparency. Overall, this work contributes to understanding the ambiguous role of technological change in HR, which promises to augment predictive capabilities yet serves the ends of efficiency and rationalisation.
• Dual-concentration PVA hydrogel brain phantom for neurosurgical training. Evers, Lea; Seidensticker, Franziska; Evers, Lukas Friedrich; Friedrich, Thomas; Behrends, André; Männel, Georg; Buschschlüter, Steffen; Schetelig, Daniel; Bonsanto, Matteo Mario; Kren, Jessica; Aderhold, Eric; Kundrat, Dennis; Buzug, Thorsten M. (2026). (Vol. 8) 2742.
• Development of parameterized unit cells for the elasticity modulation of 3D-printed midsoles. Friedrich, Thomas; Peuckert, Lea; Seidensticker, Franziska; Evers, Lea; Buzug, Thorsten M. (2026). (Vol. 8) 2743.
• The distribution of integer partitions in human genome-wide genealogies reflects gene flow from a super-archaic lineage. Mackintosh, Alexander (2026).

  Several recent studies have found evidence for ancient gene flow between the ancestors of modern humans and an unsampled super-archaic lineage. Here we present a new, simple approach for characterising this process given genome-wide genealogies sampled from a single population. We summarise genealogies as distributions of integer partitions and show that this captures the temporal signal of tree imbalance left by ancient gene flow. We analyse genealogies from modern humans and find that the integer partition distributions are inconsistent with a history of panmixia but can be explained by gene flow from a super-archaic lineage. Our analysis favours a model of continuous gene flow over pulse-admixture and also recovers a bottleneck in the ancestors of modern humans. This work highlights a clear signal of ancient structure in genealogies of modern humans and provides an inference approach that complements existing methods.Competing Interest StatementThe authors have declared no competing interest.
• Phantom-based Training of Real-Time Instrument Tracking and Navigation for Neurosurgical Applications. Eberenz, Alexandra; Evers, Lea; Schetelig, Daniel; Bonsanto, Matteo Mario; Kren, Jessica; Krusen, Marius; Kundrat, Dennis (2026). (Vol. 8) 2728.
• „Wir sind zum Nadelöhr geworden“: Interview: Wie openDesk künftig an Unternehmen vermarktet wird. Wölbert, Christian (2026). (19) 34–35.

  Austauschbare Komponenten, neues Vertriebsmodell: Bei der Microsoft-Alternative openDesk stehen Änderungen an. Details und Preise verrät das ZenDiS im Interview.
• Bundes-Office läuft auf Mini-PCs: openDesk auf einem Kubernetes-Cluster installieren. Dierking, Niklas (2026). (19) 28–33.

  Die Community Edition von openDesk lässt sich selbst betreiben, aber das ist nicht so einfach. So bauen Sie einen Kubernetes-Cluster und installieren die Suite.
• SECURE FEDERATED INTRUSION DETECTION USING HOMOMORPHIC ENCRYPTION: A COMPARATIVE STUDY WITH ENSEMBLE LEARNING. Sadaf, Aasim Zafar; Luqman, Mohammad (2026). 18(4) 97–115.

  The rapid growth of the Internet of Things (IoT) has also resulted in the increase of the demand in the intrusion detection systems, which can detect suspicious activity and keep the information confidential. The traditional centralized machine learning systems involve attaching the data of the distributed devices to a centralized server thus placing them at a risk of being stolen. Federated Learning (FL) may help overcome this difficulty and assist in a distributed model training process without sharing raw client data. Nevertheless, updated versions of models that are transferred in the process of training are susceptible to poisoning or inference attacks at communication and aggregation. This paper proposed a federated intrusion detection system that is secure and involves implementation of Homomorphic Encryption (HE), in this case CKKS scheme, to provide model updates protection in aggregation process. The CICIoT2023 dataset was used in extensive experimentation of the proposed framework in terms of comparing with the classical machine learning baselines and experiences in using ensembles. Our findings show that the centralized Random Forest model with optimal accuracy of 98.57% worked best and the proposed Federated Learning models worked well with the standard FL performance of 79.54% and the encrypted FL+HE model performed with an accuracy of 79.39%. These are some results that demonstrate how Homomorphic Encryption enables the security and confidentiality of model aggregation a significant effect to model detection (reducing by only 0.15 percent), which provides a strong privacy-preserving security solution to decentralized IoT networks.
• Efficacy and safety of low-dose nivolumab in treatment of advanced solid tumors: a retrospective audit from resource-constrained settings. Kumar, Amit; Kapoor, Akhil; Noronha, Vanita; Patil, Vijay M; Joshi, Amit; Menon, Nandini; Janu, Amit; Mahajan, Abhishek; Rajendra, Akhil; Agarawal, Amit; Khaddar, Satvik; Rajpurohit, Anu; Kashyap, Lakhan; Srikant, Anne; Panda, Gautam; Kota, Kishore Kumar; Talreja, Vikas; Prabhash, Kumar (2024). 14(1) 70–76.

  Background: Immunotherapy has improved outcomes in many advanced solid tumors. In resource-constrained settings, less than 2% of patients can afford standard dose immunotherapy. A recent phase II study showed the efficacy of low-dose immunotherapy in this setting. We used low-dose immunotherapy on a compassionate basis in patients who had progressed on available standard treatment options and standard dose immunotherapy was not feasible. Patients and methods: We retrospectively collected data from the medical oncology department for consecutive patients who had initially received standard lines of therapy followed by low-dose immunotherapy (nivolumab 40 mg) on a compassionate basis. The demographic details, histology, prior treatment, clinical and radiological response, date of disease progression, date of death, and toxicity data were collected. Results: A total of 54 consecutive patients, who received low-dose immunotherapy with nivolumab from January 1, 2018 to February 14, 2020, were included in this analysis; 4 patients were not radiologically evaluable. The median age was 50.4 years (range 35-74 years), male:female ratio was 6:1. The most common comorbidities were hypertension and diabetes seen in 12 (22.2%) and 6 (11.1%) patients, respectively. The majority of the patients (70.4%) were of head and neck cancer. The median follow-up was 4.5 months (range 0.5-11.7). Clinical benefit was observed in 18 (33.3%) patients. Partial response and stable disease were achieved in 9 (16.7%) and 5 (9.3%) patients, respectively. Median survival was not reached for these patients. Six months progression-free survival and overall survival were 100 versus 8.7% (hazard ratio [HR] 0.05, 95% confidence interval [CI]: 0.01-0.36; p = 0.003) and 100 versus 29.7% (HR 0.03, 95% CI: 0.00-0.95; p = 0.047), respectively, for responders and nonresponders. The side effects were manageable.
• MONALEESA-2 trial—a beacon of hope. Tripathi, Mayank; Vineet, Kumar (2024). 87(1) 221–222.
• Effects of viral infections like COVID-19 on head and neck cancers: the role of neutrophil-lymphocyte counts and ratios. Sarkar, Sunayana R; Singhavi, Hitesh R; Das, Abhishek; Dhal, Ipsita; Shukla, Shreya; Nanda, Sambit S; Mishra, Aseem; Lamba, Komal; Mishra, Anamika (2024). 16(6) e61733.

  Background: Over the last three years, the coronavirus disease 2019 (COVID-19), caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has had a global impact. COVID-19 has led to diagnostic and treatment delays in head and neck squamous cell cancers (HNSCCs). Both cancer and COVID-19 trigger systemic inflammatory responses that can result in cytokine storms, creating a favorable tumor microenvironment that supports tumor growth. Various studies have shown a positive association between increasing neutrophil-to-lymphocyte ratio (NLR) and disease severity in COVID-19. Studies have also shown that high NLR is associated with poor survival outcomes in cancer patients. Our aim is to investigate whether an increased NLR is linked to rapid tumor progression in patients with HNSCC who have also been affected by infections like COVID-19 in the pre-operative period. Methods: This was a retrospective analysis of patients of HNSCC who were scheduled for surgery and had contracted COVID-19 in their pre-operative period between April 2021 and May 2021. The study analyzed pre- and post-COVID NLR in relation to disease progression in HNSCC. Statistical analysis was presented as an interquartile range and numbered with the percentage. Statistical Package for the Social Sciences (IBM SPSS Statistics for Windows, IBM Corp., Version 26.0, Armonk, NY) was utilized for the analysis. Results: We evaluated 200 operable cases of which 38/200 (20%) patients with HNSCC were COVID-19 positive. Out of those COVID-19-positive patients, 27/38 (71%) patients got operated. Around, 11/38 (28.9%) patients were inoperable. And, 14/27 (53.8%) operated patients also had a change in treatment plan. The mean duration from the joint clinic treatment plan to the date of surgery was 25.18 days. Patients who had contracted COVID-19 and had a change in their treatment plan due to disease progression exhibited mean NLR values of 3.84 (pre-COVID) and 11.11 (post-COVID), with respective medians of 3.04 and 10.50. These differences showed a statistically significant p-value of 0.000. In contrast, patients who had no change in treatment plan displayed mean NLR values of 4.51 (pre-COVID) and 9.70 (post-COVID), with respective medians of 3.47 and 3.42, resulting in with a non-significant p-value of 0.082. Conclusion: This is a one-of-its-kind study that has evaluated the role of elevated NLR in patients with a COVID-19 virus infection and its relationship with the clinical progression of the disease. The findings suggest that elevated NLR in patients with HNSCC, along with concurrent SARS-CoV2 infection, may contribute to accelerated disease progression with an increase in tumor burden and nodal metastasis.
• Large urinary bladder leiomyoma mimicking malignancy: using diffusion-weighted imaging as a problem solving tool. Pande, Pooja; Singh, Satyendra N.; Manikandan, M.V (2024). 81(6) 735–738.

  Benign tumors of the urinary bladder are rare and while leiomyomas are the most common type of benign mesenchymal tumors of the bladder, their incidence is low, and most of these tumors are small and asymptomatic. We present a rare case of a large symptomatic urinary bladder leiomyoma in a young female patient referred to a tertiary cancer hospital for management after a suspicion for malignant involvement was raised on initial evaluation, and subsequently, a magnetic resonance imaging was performed. Diffusion-weighted imaging was used as a problem-solving tool to differentiate the tumor from a more common malignant pathology arising from the urinary bladder.
• Evaluation and management of unresectable hepatocellular carcinoma: multidisciplinary Indian consensus statements from a delphi panel. Ramaswamy, Anant; Shukla, Akash; Engineer, Reena; Sundaram, Sridhar; Srinivas, Sujay; Kulkarni, Suyash; Patkar, Shraddha; Baijal, Sanjay; Kale, Aditya; Kapoor, Akhil; Mukund, Amar; Choudhari, Amit; Rauthan, Amit; Mathew, Ashwathy Susan; Panchal, Rushi; Bhattacharya, Kausik; Patil, Prachi; Shetty, Nitin; Gala, Kunal; Kumar, Lijesh; Thiruchunapalli, Deepashree; Kalra, Naveen; Sahoo, Tarini Prasad; Krishna, M Vamshi; Lavingia, Viraj; Mohanka, Ravi; Talwar, Vineet; Ostwal, Vikas; Bhargava, Prabhat; Poddar, Jyoti; Singal, Amit; Goel, Mahesh (2024). 14(2) 123–134.

  AbstractBackgroundIndia, like many parts of Asia, likely faces a high burden of hepatocellular carcinoma (HCC), though large-scale data on etiology, presentation, and outcomes are lacking. There appears to be a predominance of unresectable, advanced-stage HCC at presentation in India with variable level of expertise in India to manage these scenarios. This publication summarizes the latest evidence with cognizance of the unique challenges faced in India by treating clinicians.MethodsA multidisciplinary panel of medical oncologists, gastroenterologists, hepatologists, interventional radiologists, and hepatobiliary surgical oncologists held a meeting in June 2022 and reviewed the evidence available for management of HCC. The meeting concentrated on the recognition and management of HCC not amenable to surgical approaches in the Indian context. A literature review of these aspects of management was conducted and consensus statements with level of evidence and grades of recommendation were prepared by individual specialists in each field. Statements were evaluated by the modified Delphi method.Key Content and FindingsThe panel comprising 22 experts formulated 40 consensus statements with regard to defining unresectable HCC, optimization of underlying conditions prior to management, rationale use of various liver-directed therapies (LDTs) in unresectable HCC, and systemic therapeutic options in this group of patients.ConclusionOur consensus statements offer practical, yet evidence-based management guidelines for treating unresectable HCC in the Indian context. There is an emphasis on the crucial need for combining available approaches for LDT, even if less well studied though possibly effective, with standard systemic therapy.
• Management of non-IDC histology breast cancer Kapoor, Ankita Rungta; Giridhar, Prashanth (S. Mallick; C. K. Sharma, eds.) (2024). 401–411.

  Non-IDC histology breast cancer constitutes 10–15% of breast cancers. Invasive lobular carcinoma is the most common variant while the metaplastic variant appears to be the most aggressive. There appear to be variations in terms of epidemiology, prognosis and patterns of care amongst different histology. The chapter summarises in brief common non-IDC breast cancer management. Unique points in individual cancers pertaining to epidemiology, pathology, genetics, pattern of presentation and pattern of management have been summarised pointwise.
• Factors associated with mandibular deviation and proposed classification and treatment guidelines for applying mandibular guidance: A retrospective analysis of 185 patients with segmental mandibulectomy. Gupta, Lokendra; Mishra, Aseem; Gurav, Sandeep V.; Dholam, Kanchan; Pal, Ankita; Kumar, Avinash (2025). 134(5) 1998–2006.

  Statement of problem Mandibular guidance therapy is the preferred treatment for patients with segmental mandibulectomy after oncological surgeries. Clinicians face difficulty in decision making and delivering appropriate prosthetic treatment for the rehabilitation of these patients because of the lack of published information. Purpose The purpose of this retrospective analysis was to evaluate the factors associated with mandibular deviation and to introduce a classification system of mandibular deviation and prosthetic guidelines for rehabilitating patients with segmental mandibulectomy using a mandibular guidance appliance (MGA). Material and methods A total of 185 patients with segmental mandibulectomies without bony reconstruction were evaluated from July 2019 to July 2022 for factors affecting the mandibular deviation and the feasibility of rehabilitating these patients with various types of MGA. Patients reconstructed with a free fibula osteocutaneous flap and those who underwent marginal mandibulectomies without mandibular deviation were excluded from the analysis. Based on the extent of mandibular deviation, the condition of oral tissues, and the functional activity, patients were classified into 1 of 5 classes and treated with an appropriate MGA. Data were analyzed with the Kruskal-Wallis and Fisher exact tests (α=.05). Results Of 185 patients, 45 (24.3%) showed no mandibular deviation and were classified into class I without the need for a guidance appliance; 114 (61.6%) showed mild mandibular deviation, were classified into class II, and were treated with a mandibular guide plane prosthesis (MGPP); 7 (3.8%) showed moderate mandibular deviation, were classified into class III, and were treated with a progressive mandibular guide plane prosthesis (Progressive MGPP); 5 (2.7%) showed severe mandibular deviation with fibrosis, were classified into class IV, and were treated with an occlusal ramp prosthesis; and 14 (7.6%) showed compromised oral conditions, were classified into class V, and did not receive any type of MGA. Patients with M0, poorly differentiated squamous cell carcinoma and those who had received radiotherapy showed more mandibular deviation (P<.05). The degree of mandibular deviation increased from Class I to Class IV and was significantly associated with the time gap between surgical intervention and MGA delivery (P<.05). Conclusions Radiotherapy and delay in delivering the MGA had a significant effect on mandibular deviation. The proposed classification and prosthetic guidelines were based on the mandibular deviation and will help clinicians in decision making and planning treatment before delivering the MGA.
• Neuroendocrine carcinoma of the gall bladder: a clinicopathological report of 56 Cases from a tertiary care cancer center in North India. Pal, Paramita R.; Paul, Paramita; Patne, Shashikant C. U.; Chowdhury, Zachariah; Dhal, Ipsita; Haiyat, Sadaf (2025). 21(5) 1052–1058.
• Metaplastic carcinoma of breast with heterologous mesenchymal differentiation (carcinosarcoma) having an endothelial component: a case report. Dokania, Shubham; Pujari, Lincoln; Giridhar, Prashanth; Shinghal, Abhishek; Kapoor, Ankita Rungta; Datta, Avradeep; Chowdhury, Zachariah; Gupta, Anuj; Tripathi, Mayank; Mondal, Pritam; Pradhan, Satyajit (2025). 19(1) 470-.

  Background Metaplastic breast cancer with heterologous mesenchymal differentiation, known earlier as carcinosarcoma, consists of both infiltrating ductal carcinoma cells and mesenchymal cells, and is associated with an aggressive course. The mesenchymal component is rarely endothelial, with only two previously reported cases. The present case is the third among those. Moreover, the disease outcome was good, unlike the usual course of carcinosarcoma. Case presentation A 59-year-old multiparous woman of Indo-aryan ethnicity developed a lump in her left breast and was diagnosed with breast carcinosarcoma having an endothelial component, with the help of histopathological examination and immunohistochemistry. The tumor was surgically removed; then the patient received adjuvant chemotherapy, epirubicin, and cyclophosphamide, followed by adjuvant radiotherapy to the whole breast, followed by tumor bed boost. The patient was clinic-radiologically disease-free even at 26 months post-treatment. Conclusion Surgery followed by adjuvant chemotherapy and radiotherapy gives better outcomes compared with surgery alone, with a doubtful role of neoadjuvant chemotherapy. Targeted therapies can be considered in patients not responding to conventional treatment.
• Lorlatinib in TKI-naïve patients with advanced ALK-positive non-small cell lung cancer (NSCLC) from India. Batra, Ullas; Roy, Somnath; Menon, Nandini Sharrel; Warrier, Narayanankutty Edavalath; Kapoor, Akhil; Rajpurohit, Sajjan; Rajappa, Senthill J.; Thirumalairaj, Raja; Advani, Suresh Hariram; Sehra, Nishtha; Jain, Ankita (2025). 43(Suppl.16) e20679-.

  Background: Lorlatinib is a novel brain penetrant 3rd generation anaplastic lymphoma kinase (ALK)- inhibitor, approved as frontline & subsequent line therapy in ALK-rearranged advanced non-small cell lung cancer (NSCLC). However, data on its safety and effectiveness as first-line (1L) therapy in the Indian population remains limited. This study presents an interim analysis of real-world data of 1L Lorlatinib in TKI-naïve ALK-positive advanced NSCLC patients in India. Methods: This is an ongoing ambispective, non-interventional real-world study involving 9 centers across India. All patients diagnosed with ALK-positive advanced NSCLC with or without brain metastases, TKI naïve, receiving lorlatinib in the first line setting & willing to participate can be enrolled. Primary objective of the study is 18-month Progression Free Survival (PFS) rate. This interim analysis has been conducted to assess early response and safety outcomes in the first 51 patients enrolled. A descriptive analysis was conducted on the entire cohort of 51 patients however, Objective Response rate (ORR) and early safety was analyzed for the retrospective cohort & for the prospective patients with at least 1 follow-up (n = 39). Results: From May 2024 - Dec 2024, a total of 51 patients (36 retrospective & 15 prospective) were enrolled in the study. The median age observed was 51 years & Male : Female ratio was 29:22. 94.1% (n = 48) had metastatic disease at the time of Lorlatinib initiation and 49% (n = 25) had brain metastases at baseline. 7.8% patients had received prior brain radiotherapy & 72.5% had an ECOG performance-status score of 1. At median follow up of 8 months within the cohort of 39 patients, the ORR was 74.4% (n = 30 of 39). The best response for 66.7% (n = 26) patients was partial response (PR), 15.3% (n = 6) stable disease (SD), 10.3% (n = 4) complete response (CR) and 7.7% (n = 3) reported progression.17 patients were evaluated for intracranial response and the Intra-cranial Objective response rate (IC-ORR) was 70.6%. 21.1% (n = 4) achieved CR in the brain, 42.1% (n = 8) had PR & 15.8% (n = 3) had SD. On safety analysis, 84.6% (n=33) reported at least one adverse event (AE) of any grade. Hypertriglyceridemia (36.4%) was the most reported AE followed by hypercholesterolemia (27.3%). Pedal edema was observed in 18.2% & weight gain in 15.2% patients. Mood effects were observed in 2 patients. Majority of AEs were mild to moderate (Grade 1/2) in severity & managed either with concomitant medication or resolved on their own. 10.3% (n = 4 of 39) required temporary dose interruptions and 10.3% (n = 4 of 39) patients had permanent treatment discontinuation ? 3 had disease progression and 1 due to AE. No dose reductions were reported. Conclusions: Consistent with CROWN trial data, the preliminary results from this real-world study with 1L Lorlatinib in ALK positive advanced NSCLC in the Indian population supports its effectiveness as well as tolerability profile.
• Evolution of radiation therapy strategies Nanda, Sambit Swarup; Mallick, Supriya; Giridhar, Prashanth (R. Madan; S. Goyal; S. Mallick, eds.) (2025). 13–21. Springer.

  Radiation therapy in pediatric tumors has undergone a spectral change from conventional two-dimensional radiotherapy to intensity-modulated radiotherapy (IMRT) over last few decades. The complexity of pediatric diseases and its varied presentations have put the focus on the technological advancement to deal with site and disease specific challenges. The radiation therapy strategy has been driven by attempts to improve therapeutic index. This involves improving the disease control by exactly characterizing location and extent of the disease. The integration of technological advancements, such as computed tomography (CT) scans, magnetic resonance imaging (MRI), and positron emission tomography (PET) scans, has enabled radiation oncologists to define the structural and functional aspects of every tumor. The use of these modern imaging techniques and improved pathological classification of pediatric tumors helped oncologists to characterize these tumors according to their nature and predict prognosis. Furthermore, it has helped in predicting the recurrence pattern in various type of tumors. These factors, such as the nature of tumor, its extent, pattern of presentation, and recurrence, have dictated the radiotherapy techniques.
• Investigating inter-layer crosslinking of alginate-gelatine hydrogels to modify layer adhesion. Behrends, André; Evers, Lea; Dell, Annika; Leonov, Roman; Wendt, Dennis; Friedrich, Thomas; Buzug, Thorsten (2025). (Vol. 7) 2109.
• ICRI Case of Week. Shukla, Shreya (2025). 1–12.
• Saatgutbibliothek und Nachhaltigkeit - Eine Untersuchung zur Wahrnehmung der Bibliotheksnutzer*innen. Bachelorarbeit. Technical Report (PhD dissertation), Köroglu, Selin (2025).

  Zusammenfassung: Diese Arbeit untersucht, wie Bibliotheksnutzer*innen das Angebot der Saatgutbibliothek im Kontext der Nachhaltigkeit wahrnehmen. Zur Beantwortung der Forschungsfrage wurden Leitfadeninterviews mit den Bibliotheksnutzer*innen durchgeführt. Ziel der Analyse war es herauszufinden, inwiefern das Angebot als nachhaltig wahrgenommen wird oder ob es eher als niederschwelliges Tauschangebot verstanden wird. Die Ergebnisse der Arbeit zeigen, dass die Befragten die Saatgutbibliothek überwiegend als nachhaltiges Angebot einschätzen, diese Wahrnehmung jedoch mehr mit ihrem eigenen Handeln verbinden, während ökologische Hintergründe weniger im Fokus stehen. Aus diesen Erkenntnissen wurden Empfehlungen für die Bibliothekarische Praxis abgeleitet, die Vorschlagen, das Angebot stärker mit Informationen zu ökologischen Themen zu verbinden und den Austausch zwischen den Bibliotheksnutzer*innen zu fördern. Abstract: This Bachelor Thesis examines how library users perceive the seed libraries offerings in the context of sustainability. To answer the research question, interviews were conducted with library users. The aim of the analysis was to determine to what extent the seed library is perceived as a sustainable initiative or rather understood as an easily accessible exchange service. The findings show that respondents predominantly view the seed library as a sustainable offering, though they tend to associate this perception more with their own actions, while ecological aspects are less in focus. Based on these insights, recommendations for library practice were developed, suggesting that the offering should be more closely linked to information on ecological topic and that exchange among library users should be further encouraged.
• Evaluating the clinico-pathological features including the immunohistochemical and molecular landscape of synovial sarcoma cases from a tertiary care cancer referral centre in India. Rai, Himani; Dhal, Ipsita; Chowdhury, Zachariah; C U Patne, Shashikant; Kapoor, Akhil; Gupta, Anuj; Nanda, Sambit; Haiyat, Sadaf; Paul, Paramita; Mukherji, Ashutosh; Singh, Rajesh B.; Singh, Satyendra Narayan; Pandey, Durgatosh (2025). 25(1) 1445-.

  Background: Synovial sarcoma (SS) is a malignant mesenchymal neoplasm with variable epithelial differentiation, with a propensity to occur in young adults. The pathognomonic t(X;18) chromosomal translocation and subsequent development of the SS18:SSX fusion oncogenes are the driver of the distinct genomic features. Aim: To study the Clinicopathological, immunohistochemical and molecular features of SS occurring in all the organ systems. Method: A retrospective observational study was conducted over a period of 4 years at a tertiary cancer centre. Result: One hundred eight patients were included in the study based on exclusion and inclusion criteria. The median age of patients was 30.5 years and mean tumor diameter was 10.5 cm. Most common site was lower limb followed by lung, and arm. 50 patients underwent surgery and 49 patients received adjuvant chemotherapy or radiotherapy. 87 patients (81%) presented with monophasic subtype and 21 (19%) with biphasic subtype. The most helpful immunohistochemical markers for diagnosis and exclusion of close differentials were TLE1, EMA, Pancytokeratin, S-100, BCL2, and CD99. Molecular diagnostic confirmation was attained in 10 out of 15 patients. On median follow-up of 7.58 months, mean 4-year overall survival of the patients was 91.39%. Conclusion: Meticulous pathologic evaluation and awareness of the typical and atypical histology of SS along with the apt application of immunohistochemical marker such as TLE1 and/or cytogenetics (SYT translocation) assist in precise recognition of this not so common entity. The main therapeutic modality is surgical excision with negative margins, with the addition of radiotherapy and/or chemotherapy based on patient and tumour characteristics.
• Nachhaltige Entwicklung von Bibliotheken und Bildung für nachhaltige Entwicklung in Bibliotheken. Das Leipziger Konzept. Metz, Susanne; Friesel, Mareike; Gruhle, Cornelia; Klapperstück, Ines; Tscholitsch, Stefanie (2025). 59(6-7) 330–350.

  Zusammenfassung: Seit 2019 beschäftigen sich die Leipziger Städtischen Bibliotheken intensiv mit der Bildung für nachhaltige Entwicklung (BNE). Ziel ist es, einen ganzheitlichen BNE-Ansatz zu entwickeln und umzusetzen. BNE wird dabei nicht als ergänzendes Thema verstanden, sondern als eine Sammlung methodisch-didaktischer Ansätze, die es ermöglichen, Kompetenzen zu vermitteln, um Menschen -- einschließlich der Mitarbeitenden in Bibliotheken -- zu zukunftsfähigem Denken und Handeln zu befähigen. BNE soll nicht als glqqzusätzliches Projektgrqq neben den bestehenden Aktivitäten der Bibliothek existieren, sondern als Haltung und Anspruch in allen Bereichen und Aktivitäten der Organisation verankert werden -- wir leben, was wir vermitteln! Der Beitrag zielt darauf ab, das Vorgehen der Leipziger Städtischen Bibliotheken darzustellen, um das Ziel des Whole Institution Approach zu erreichen. Im Fokus stehen die Entwicklung und kontinuierliche Weiterentwicklung eines BNE-Konzepts, die Qualifizierung der Mitarbeitenden und die schrittweise Implementierung dieses Ansatzes. Abstract: Since 2019, Leipzig`s municipal libraries have been working on an educational program for sustainable development (ESD) with the aim to mainstreaming a holistic approach to ESD. Rather than representing an additional topic on the list, ESD is here conceived as a collection of methodological-didactic approaches to enable library users and staff to acquire skills in thinking and acting sustainably in any situation, geared towards the framing an organization-wide aspirational mind-set and attitude towards sustainability. We want to live what we preach! The article describes how Leipzig's municipal libraries are advancing to achieve a whole-institution approach, with a focus on the development of the ESD concept, ongoing qualification of employees and the progressive implementation of this holistic approach.
• Explained, yet misunderstood: How AI Literacy shapes HR Managers’ interpretation of User Interfaces in Recruiting Recommender Systems. Kalff, Yannick; Simbeck, Katharina (2025, September).

  AI-based recommender systems increasingly influence recruitment decisions. Thus, transparency and responsible adoption in Human Resource Management (HRM) are critical. This study examines how HR managers' AI literacy influences their subjective perception and objective understanding of explainable AI (XAI) elements in recruiting recommender dashboards. In an online experiment, 410 German-based HR managers compared baseline dashboards to versions enriched with three XAI styles: important features, counterfactuals, and model criteria. Our results show that the dashboards used in practice do not explain AI results and even keep AI elements opaque. However, while adding XAI features improves subjective perceptions of helpfulness and trust among users with moderate or high AI literacy, it does not increase their objective understanding. It may even reduce accurate understanding, especially with complex explanations. Only overlays of important features significantly aided the interpretations of high-literacy users. Our findings highlight that the benefits of XAI in recruitment depend on users' AI literacy, emphasizing the need for tailored explanation strategies and targeted literacy training in HRM to ensure fair, transparent, and effective adoption of AI.
• Extravasation with systemic anti-cancer directed therapy administration at daycare in a tertiary care oncology centre: Insights from a prospective observational study (EXACT study). Bipinesh, Sansar; Akhil, Kapoor; Gupta Anuj; Krishna, Mishra Bal; Arpita, Singh; Ojha Kamalkant; Rajasekhar, Dandeti (2025). 10781552251372872-.

  BackgroundEstablishing benchmarks for extravasation incidences with systemic anti-cancer therapy from various global regions is crucial. Reliable data can inform practices aimed at reducing both the occurrence and severity of extravasation events.MethodsThis prospective observational study evaluated extravasation incidences in patients receiving systemic anti-cancer therapy for solid tumors at a tertiary oncology daycare center over a period of 15 months. Multiple risk factors potentially contributing to extravasation and influencing its severity were systematically recorded and analyzed.ResultsOut of 66,540 infusions, a total of 58 extravasation cases were identified, resulting in an overall incidence of 0.087%. The extravasation incidence was 0.13% for vesicant drugs and 0.045% for irritant drugs. Specifically, DNA-binding vesicants had an incidence of 0.2%, while non-DNA binding vesicants had an incidence of 0.11%. The predominant symptom reported was infusion site swelling (86%), followed by pain (43%) and erythema (36%). Grade 3 extravasation occurred in 13 cases (22.4%), with vesicants responsible for all but one event. Median symptom resolution time was 20 days overall, extending to 40 days in grade 3 cases. Notably, the occurrence of symptoms either during infusion or within 6 h post-infusion significantly correlated with milder grade 1 extravasations, lower incidence of severe grade 3 cases, and quicker symptom resolution within three weeks.ConclusionsDaycare oncology centers should implement standardized protocols for systemic therapy administration, emphasizing preventive strategies and prompt identification and management of extravasation to reduce associated morbidity.
• Enhancing the sepsis chain of survival: a call for practical implementation and adherence monitoring. Maurya, Prakriti; Ghatak, Tanmoy; Maurya, Prateek (2025). 53(12) e2780-e2781.
• Accommodating seed libraries into public libraries: A platform to address food insecurity in India. Bhanu, Mariam; Dhanyasree, V. K. (2025). 44(5) 662–677.

  There are several initiatives adopted by public libraries to address issues on food insecurity which includes public food programs, community-based agricultural programmes, community food gardens, and seed libraries. The need of a seed library in the community is not just about promoting agricultural practices, it also helps to address the rising food insecurity and hunger issues prevailing in the society. This paper explores how seed libraries could be incorporated within public libraries and their scope in Indian context. For the purpose of the study, previous articles on seed libraries were analyzed to understand its functions and operations. The ``Annapurna Seed Library'' in Assam is selected to provide insight on the scope for seed libraries in India and how it could be implemented in other states as well.
• P3.18.34 TACTI-004, a Phase 3 Trial of Eftilagimod Alfa Plus Pembrolizumab (P) + Chemotherapy (C) vs Placebo + P + C in 1St Line NSCLC. Sebastian, M.; Nordman, I.; Ürün, Y.; Voon, P.J; Isla, D.; Vera, K.; Orlandi, F.; Sansar, B.; Winckels, S.; Mueller, C.; Triebel, F. (2025). 20(10, Supplement 1) S559-.

  Eftilagimod alfa (E), an antigen presenting cell activator, binds to a subset of MHC class II molecules to mediate T cell (CD4/CD8) recruitment/activation. Prior studies in first line (1L) non-small cell lung cancer (NSCLC) (TACTI-002 [NCT03625323]: combining E + pembrolizumab (P); INSIGHT-003 [NCT03252938] combining E with chemotherapy + P [SoC]) showed encouraging efficacy results across all PD-L1 strata & excellent safety profiles. TACTI-004 is a double-blinded, randomized, placebo-controlled phase 3 study testing E + SoC vs. placebo + SoC in 1L NSCLC patients (pts).
• Quality of life (QoL) among cancer ostomized patients – a cross-sectional study at a tertiary cancer centre. Sharma, Rajni; Kannojia, Pooja (2025). 4.

  Background: Cancer treatment often necessitates surgical interventions, including stoma formation (colostomy, ileostomy, or urostomy), which significantly impacts a patient's quality of life (QoL). Ostomized patients face a unique set of challenges encompassing physical, psychological, social, and emotional aspects. While numerous studies have investigated these challenges, there is a lack of comprehensive research focusing on the QoL of cancer patients with stomas in India. Understanding the factors influencing the QoL of these patients is critical for developing interventions tailored to their needs. This study aims to evaluate the QoL of cancer patients with ostomies and identify key factors affecting their overall well-being. Methods:Study Setting: This cross-sectional study was conducted at the Mahamana Pandit Madan Mohan Malaviya Cancer Centre (MPMMCC), a leading tertiary cancer care facility in Varanasi, India, specializing in cancer treatment, including ostomy procedures. The study was conducted over three months, from March 1, 2021, to July 31, 2021. Study Population: The study sample included 100 ostomates, both outpatient and inpatient, from MPMMCC. Participants were adults (18 years or older) who had undergone colostomy, ileostomy, or urostomy and were willing to participate in the study. Individuals who were unwilling to participate were excluded.
• Modelling Model Uncertainties Ontologically. Stappel, Mirjam; Mossakowski, Till; Neuhaus, Fabian; Berendes, Sarah (2025).
• A Survey on Resource Management Solutions, Challenges, and Emerging Opportunities in Fog Computing Ghoneim, Firas (2025).
• Vlasov methods in space physics and astrophysics. Palmroth, Minna; Ganse, Urs; Pfau-Kempf, Yann; Battarbee, Markus; Alho, Markku; Nättilä, Joonas; Zaitsev, Ivan; Cozzani, Giulia; Papadakis, Konstantinos; Kotipalo, Leo; Zhou, Hongyang; Turc, Lucile; Hoilijoki, Sanni; Grandin, Maxime; Pänkäläinen, Lauri; Sandroos, Arto; von Alfthan, Sebastian (2025). 11(1) 3.

  This paper reviews Vlasov-based numerical methods used to model plasma in space physics and astrophysics. Plasma consists of collectively behaving charged particles that form the major part of baryonic matter in the Universe. Many physical concepts ranging from our own planetary environment to the Solar system and beyond can be understood in terms of kinetic plasma physics, represented by the Vlasov equation. We introduce the physical basis for the Vlasov systems, and then outline the associated numerical methods that are typically used. A particular application of the Vlasov system is Vlasiator, the world's first global hybrid-Vlasov simulation for the Earth's magnetic domain, the magnetosphere. We introduce the design strategies for Vlasiator and outline its numerical concepts ranging from solvers to coupling schemes. We review Vlasiator's parallelisation methods and introduce the used high-performance computing (HPC) techniques. A short review of verification, validation, and physical results is included. The purpose of the paper is to present the Vlasov equation and its use in numerical modelling, introduce an example implementation, and to illustrate that even with massive computational challenges, an accurate description of physics is highly rewarding as it allows to significantly advance our understanding of complex plasma systems. As an update to the previous paper in this series, we especially highlight latest trends in HPC including graphics processing units (GPUs) and emerging applications in astrophysical plasmas.
• Pediatric scapular cavernous hemangioma presenting with kasabach–merritt syndrome and controlled by preoperative angioembolization: a case report. Pande, Pooja; Bhame, Suraj; Bansal, Harshit; Ranjan, Raghwesh; Saha, Soumitra (2025).

  Intraosseous hemangioma is a common and benign vascular tumor with a propensity to occur in any bone of the body. Although the most common skeletal sites are the craniofacial bones and the spine, hemangioma of the scapula is a rare occurrence, which is rarer in the pediatric population. Kasabach–Merritt syndrome (KMS) is characterized by the combination of a rapidly growing vascular tumor, thrombocytopenia, microangiopathic hemolytic anemia, and consumptive coagulopathy. This condition can cause massive bleeding even after minor trauma and immediate operative management is usually contraindicated. We report a rare case of KMS in an 8-year-old girl with cavernous hemangioma of the scapula presenting with progressively increasing shoulder mass, thrombocytopenia, and serially falling hemoglobin levels. She was treated with preoperative angioembolization to manage the consumptive coagulopathy followed by surgery poststabilization. Intraosseous hemangiomas, while benign, can show aggressive features on imaging and angioembolization can be a life-saving tool in the management of vascular tumors presenting with consumptive coagulopathy. Intraosseous hemangiomas, while benign, can show aggressive features on imaging and angioembolization can be a life-saving tool in the management of vascular tumors presenting with consumptive coagulopathy.
• The Elgar Companion to Regulating Platform Work: Insights from the Food Delivery Sector Vandaele, Kurt; Rainone, Silvia (2025). Edward Elgar Publishing, Cheltenham.

  Multidisciplinary in scope, The Elgar Companion to Regulating Platform Work comprehensively analyses the dynamics and trends of the app-based food delivery sector in the platform economy. Adopting a comparative approach, it examines the regulatory developments in the field at EU level and beyond.
• The outlandish brain tumor: case of the rare intracranial chondrosarcoma. Shukla, Shreya; Sahu, Arpita; Sridhar, Epari (2025). 73(3) 623–626.
• SL-173 Sigma’s verdict: a six sigma deep dive into tumor marker’s analytical quality at a tertiary care cancer hospital. Ojha, Kamalkant; Kailani, Shraddha; Gavel, Pratibha; Kumar, Kundan; Mohapatra, Nirupam; Pandey, Durgesh (2025). 40(Suppl.1) S83.

  Quality control is a crucial step in ensuring the reliability of analysis results. Our approach to six sigma, a performance management tool designed to improve the precision and accuracy of results by evaluating how many standard deviations can fit within the tolerance of the process. The aim of our study was to evaluate the quality of a number of tumor markers based on the six-sigma approach and the CLIA requirements criteria. In this study the results of internal quality control of 4 tumor markers (CA-125, AFP, BHCG, and CEA) in two analyzers over a period of 6 months from January 2025 to June 2025, using the Six Sigma approach and CLIA requirement is observed. Sigma metrics for CEA, Beta- HCG were exceptional (i.e. >6) while for CA-125 & AFP the metrics were between 4 to 6. The application of the Six Sigma approach in medical laboratory aims to significantly enhance the analytical quality of results. To optimize quality control (QC) rules despite significant progress, the ultimate goal of achieving a sigma score of 6 remains a challenge. Implementing robust quality control plans is an essential step towards achieving this idea.
• The Nirmiti application: An innovative tool for extending CanReg5 analyses to cancer mortality and paediatric cancer. Sawant, Pratik; Saoba, Sushama; Kadam, Prithviraj; Gupta, Deepak; Ponnada, Adarsh Kumar; Khanna, Divya; Perera, Suraj; Tshomo, Ugyen; Ervik, Morten; Mery, Leslie; Bray, Freddie; Budukh, Atul (2025). 157(1) 161–169.

  Abstract The International Agency for Research on Cancer (IARC) Regional Hub in Mumbai provides technical support to population-based cancer registries (PBCRs) in South and South-East Asian (SSEA) countries. For data management and incidence rate table generation, the Hub recommends CanReg5, an open-source registry software developed by IARC, to all PBCRs seeking support from it. However, CanReg5 is limited in generating mortality and paediatric cancer incidence tables. Several SSEA cancer registries requested the Hub to develop practical solutions to facilitate the generation of cancer rates statistics. The IARC Regional Hub, in Mumbai, subsequently developed Nirmiti, an innovative web application which is capable of generating incidence, mortality, and paediatric cancer rates based on provided input data. The application accepts registry data in a specific format and generates required tables according to the selected options; users can input data from CanReg5 or other software into Nirmiti for processing. Nirmiti generates childhood cancer rates for age-groups 0?14 and 0?19, based on the 12 main groups and 47 subgroups of the International Incidence of Childhood Cancer, Volume 3, and is freely available to cancer registries upon request. The application has been successfully utilized by PBCRs in India, Sri Lanka, and Bhutan.
• Response evaluation criteria in grade 1/2 neuroendocrine tumors (RECIN). Aggarwal, Piyush; Satapathy, Swayamjeet; Chandekar, Kunal R.; Sood, Ashwani (2025). 56(1) 22–30.

  Accurate response assessment in well-differentiated grade 1/2 neuroendocrine tumors (NETs) remains a major clinical challenge. Conventional size-based radiographic criteria such as Response Evaluation Criteria in Solid Tumors (RECIST) 1.1 often fail to capture the slow, indolent nature of NETs. In these tumors, meaningful survival benefits, particularly after peptide receptor radionuclide therapy (PRRT) with [177Lu]Lu-DOTATATE, occur without significant tumor shrinkage, while treatment-related necrotic or inflammatory changes can mimic progression. Several modified anatomical criteria, including Choi and mRECIST, have attempted to address these limitations, but results have been inconsistent and largely retrospective. Somatostatin receptor (SSTR)-PET/CT with [68Ga]Ga-labeled analogues offers the opportunity to quantify biological response at the molecular level, reflecting alterations in receptor density and viable tumor burden. The Response Evaluation Criteria in Neuroendocrine Tumors (RECIN), developed from a post-hoc analysis of the phase II LuCAP trial, integrates semi-quantitative SSTR-PET parameters with conventional CT metrics. Using the summed SULpeak of up to five of the hottest lesions (up to two per organ), RECIN defines molecular partial response as a ≥25% reduction in summed SULpeak, while maintaining RECIST safeguards for progression. Applied to the prospective LuCAP trial dataset, RECIN identified additional responders, detected response earlier, and predicted progression-free survival more accurately than RECIST. By harmonizing biological and morphological information, RECIN provides a practical and reproducible framework tailored to the indolent, receptor-driven biology of NETs. Prospective multicenter validation, and correlation with longer term outcomes are needed to establish RECIN as standardized response criteria for PRRT as well as other treatment modalities for well-differentiated NETs.
• Patterns of labour unrest among app-based food delivery workers in Europe: the surprising persistence of industrial relations regimes. Stuart, Mark; Trappmann, Vera; Neumann, Denis; Joyce, Simon; Bessa, Ioulia; Umney, Charles K. Vandaele, S. Rainone (eds.) (2025). 96–113.

  This chapter examines to what extent distinct patterns of platform worker unrest are discernible across Europe through a study of app-based food delivery work. The analysis draws on data from the Leeds Index of Platform Labour Protest. The chapter employs Visser's typology of industrial relations regimes. Seemingly different patterns of protest are emerging across liberal, pluralist and social partnership countries. Mainstream unions are more prevalent in protests in social partnership countries, whereas they have a smaller presence in liberal pluralist ones. Strikes are dominant in liberal pluralist countries and in fragmented state-centred regimes; institutionalisation as a form of protest is most frequent in countries featuring social partnership and organised corporatism; and legal action is reported mostly in fragmented state-centred regimes. Several other distinctive patterns are also discussed. Hence, despite the weakly institutionalised nature of platform work, industrial relations regimes are important in understanding platform labour protest.
• Primary ovarian carcinoid associated with mature teratoma: a rare case presentation. Verma, Ajita; Paul, Paramita; Rai, Silky (2025). 23(2) 69-.

  Background Carcinoid tumors are neuroendocrine tumors, which are usually observed in the lungs and gastrointestinal tract with rare occurrence within the gynecologic system. Ovarian carcinoids form 0.1% of ovarian neoplasms and 1% of all carcinoid tumors. Due to its rarity, it becomes paramount to report this case, to identify key points of morphology and discuss its clinical course and best treatment options. We report a case of primary ovarian carcinoid arising within a mature cystic teratoma diagnosed at a cancer referral centre in North India. Case A 63-year-old postmenopausal woman, presented with complaints of abdominal pain for 2 months. A 10 × 12 cm immobile, firm to hard and nontender mass was palpable in lower abdomen, 2 cm below umbilicus. USG performed showed 8 × 11 cm mass in the right adnexa with loss of fat plane with the uterus and moderate ascites. Staging laparotomy was performed. Histopathology revealed a tumor disposed in insular and organoid patterns with largely monomorphous tumor cells suggestive of carcinoid which was ratified by immunohistochemistry. A small focus showed a teratomatous component comprising of ecto, meso and endodermal components. Post surgery, the patient is doing well without any new symptoms post one year of follow-up. Conclusion Ovarian carcinoid is a relatively rare neoplasm and awareness of this entity is essential for identifying various treatment options.
• Prevalence and patterns of polysubstance use (tobacco and other substances) and associated factors: a cross-sectional analysis in a high-risk cohort for oral cancer in Varanasi, India, with a special focus on young emerging adults. Shruti, Tulika; Sharma, Priyanka; Khanna, Divya; Ranjan, Sudhir; Khan, Aqusa; Gurushanth, Keerthi; Singh, Arjun Gurmeet; Mishra, Aseem; Shetty, Anupama; Birur, Praveen; Chaturvedi, Pankaj (2025). 27(8) 1349–1358.

  Introduction The dearth of population-based data on polysubstance use, especially in young emerging adults, presents a critical gap in understanding public health challenges, particularly in rural India, where tobacco use and oral cancer are prevalent. This study addresses this gap by investigating the prevalence and patterns of substance use, with a focus on young emerging adults (18–29 years) within a high-risk cohort for oral cancer in Varanasi, India. Aims and Methods The study involved a cross-sectional analysis of baseline data from 10 101 participants within a high-risk cohort in rural settings of the Varanasi district between December 2020 and June 2023. This region has high rates of tobacco use and oral cancer. Polysubstance use was defined as the lifetime concurrent use of two or more substances for at least a year. The study examined the prevalence of any substance use, polysubstance use, and associated sociodemographic factors. Univariable and multivariable analyses were employed to identify significant predictors. Results The prevalence of any substance use in the study population was 55.7%. Tobacco use was most prevalent (94.3%), followed by areca nut (44.8%), alcohol (6.6%), and cannabis (0.8%). Among young emerging adult substance users, the prevalence of polysubstance use was 42.6%. Predictors of polysubstance use included age, male gender, employment status, and income. Conclusions This study offers vital insights into substance use among rural Indian communities, particularly among young adults who are at a critical juncture in their lives. The findings underscore the urgent need for evidence-based strategies to address this region’s multifaceted public health challenge of polysubstance use. Implications Literature is scarce on population-based data for the prevalence and pattern of polysubstance (tobacco and other substances) use in India, both for the young and adult population. We studied the prevalence and pattern of substance use in a predominantly rural district of India, which reportedly has the second-highest burden of oral cancer among all Indian population-based cancer registries. We found that more than half (55.7%) of the study population used at least one substance; among them, nearly half (42.4%) used two or more substances. Tobacco use was the most prevalent form (94.3%), followed by areca nut use (44.8%), alcohol (6.6%), and cannabis (0.8%). Polysubstance use was prevalent among young emerging adult substance users. Age, male gender, employment, and income were predictors of polysubstance use. Distinct sociocultural factors shaping substance use in India necessitate research.
• PP-26 Metrological imperative: refining HbA1c testing through sigma metrics and uncertainty quantification. Ojha, Kamalkant; Kailani, Shraddha; Gavel, Pratibha; Kumar, Kundan; Mohapatra, Nirupam; Pandey, Durgesh (2025). 40(Suppl.1) S97.

  Abstracts of the 34th World Association of Societies of Pathology and Laboratory Medicine (WASPaLM) and 51st Association of Clinical Biochemists of India (ACBI) Congress 2025. Hemoglobin A1c test also known as glycated hemoglobin is used to measure an individual’s glucose levels. The test shows average blood glucose levels over the past 90 days, expressed as a percentage and can be used to diagnose dia betes mellitus. This study aims to assess the analytical per formance of HbA1c test using six sigma metrics and to de termine measurement uncertainty. The test was performed using HPLC METHOD and a retrospective analysis was conducted using internal and external quality control data over a period of 6 months in Biochemistry department of uncertainty and sigma metrics were found to be satisfactory is a valuable tool for improving the quality and reliability of testing encasing the variability and improvement in the accuracy of HbA1c measurements, while uncertainty helps prove analytic quality or the laboratory should use alternate methods and reagents. Using Sigma metrics and Uncertainty, we were able to identify the problematic areas as well as laboratory result.
• Potential advantage of therapeutic plasma exchange over intravenous immunoglobulin in children with axonal variant of guillain-barré syndrome: a report of six paediatric cases. Deb, Joyisa; Negi, Gita; Mohan, Aswin K.; Sharawat, Indar Kumar; Banerjee, Pradip; Chauhan, Deepali; Kaur, Daljit; Jain, Ashish (2025). 32(1) 112–117.

  Guillain-Barre syndrome (GBS) is a disease entity described in literature since 1859. It is associated with various etiological, clinical and immunological factors with prognostic predictive value. Both Intravenous immunoglobulin (IVIG) and Therapeutic Plasma Exchange (TPE) have been regarded as the first-line treatment for GBS. Certain diagnostic tools help us in early identification of GBS subtypes that may aid clinical management. Here, we have discussed six paediatric cases of GBS of Acute Motor Axonal Neuropathy (AMAN) subtype that were considered for TPE. 5 out of 6 patients were eventually weaned from mechanical ventilation and discharged from the hospital. This study emphasizes the role of TPE in management of severe IVIG refractory GBS with axonal involvement that can be beneficial to the patient. TPE may be considered early in GBS cases with axonal involvement.
• Vom Leihen und Teilen - Erfahrungen aus drei Jahren Saatgutbibliothek: 112. BiblioCon, Hamburg. Zarberg, Ilka (2024).

  In der Zentralbibliothek für Erwachsene der Stadtbibliothek Karlsruhe wurde 2021 mit der Planung einer Saatgutbibliothek begonnen, die im Februar 2022 eröffnet wurde. Sie ist für die Bürgerinnen und Bürger eine Möglichkeit, einen Beitrag zu Nachhaltigkeit und Sortenerhalt zu leisten. Es kann kostenlos und ohne Bibliotheksausweis Saatgut alter und lokaler Sorten ausgeliehen und ausgesät, später geerntet und geteilt werden. So kann ein Teil von nachhaltiger Landwirtschaft auch mit einer Re-Lokalisierung und dem Gärtnern im eigenen Garten oder Balkon oder über glqqUrban Gardeninggrqq verbunden sein. Gleichzeitig sind die Erträge aus eigenem Anbau durch Vermeidung von Transportwegen und Verpackungsmüll ein Beitrag zum Klimaschutz, durch Schadstoffarmut ein Beitrag zu gesunder Ernährung und die Begrünung im städtischen Raum ein Beitrag zum Insektenschutz. Mit dem Grundgedanken des Leihens und Teilens sorgt die Saatgutbibliothek für weniger Ungleichheiten und setzt gleich mehrere Ziele der glqqdeutschen Nachhaltigkeitsstrategiegrqq der Bundesregierung um. Die Erfahrungen aus drei Jahren zeigen eine interessante Mischung aus einem Bestreben nach Nachhaltigkeit und Klimaschutz, Kooperation, Neudenken und Neukundengewinnung. Das Projekt Saatgutbibliothek Karlsruhe ist eine Kooperation der grün-alternativen Hochschulgruppe Karlsruhe am KIT und der Stadtbibliothek Karlsruhe und soll auch in den kommenden Jahren weiterlaufen.
• AI in Test Automation: Overcoming Challenges, Embracing Imperatives. Khankhoje, Rohit (R. Khankhoje, ed.) (2024). 11(1)

  This scholarly article delves into the intersection of Artificial Intelligence (AI) and Test Automation, thoroughly examining the challenges inherent in implementing AI methodologies and elucidating imperatives critical for successful integration within contemporary software testing frameworks. The research entails a comprehensive exploration of challenges, ranging from intricacies in data quality to algorithmic biases, tool complexities, and integration challenges, drawing on empirical evidence from case studies and real-world scenarios. The paper articulates imperatives essential for overcoming challenges and ensuring the efficacy of AI in test automation. It emphasizes the significance of structured training programs, meticulous data management strategies, and the cultivation of an organizational culture conducive to the seamless integration of AI technologies. Through a rigorous analysis of successful case studies, the article provides a scholarly basis for the formulation of strategies and solutions to surmount challenges faced by organizations adopting AI in testing practices. A visual matrix aligning challenges with corresponding imperatives adds scholarly rigor to the article, offering a comprehensive framework for understanding the intricate relationships between challenges and the imperative strategies required for resolution. Furthermore, the exploration of emerging trends and innovations anticipates the future trajectory of AI-driven test automation, contributing valuable insights for strategic planning in the realm of software testing. This scholarly work underscores the importance of a systematic and informed approach to AI in Test Automation. By addressing challenges with academic rigor and embracing imperative strategies grounded in empirical evidence, organizations can position themselves at the forefront of AI driven testing practices, advancing the field with a scholarly foundation for continued exploration and innovation.
• Early Detection of Parkinson Disease through Biomedical Speech and Voice Analysis. Badhan, Pawan Kumar; Kaur, Manjeet (P. K. Badhan, ed.) (2024). 13(2)

  Parkinson's disease, widely recognized as a neurodegenerative condition characterized by subtle changes in voice, has spurred an investigation into voice analysis for diagnostic purposes. This study is dedicated to the early detection of Parkinson's disease through a comprehensive examination of biomedical speech attributes. Parameters such as fundamental frequency range, jitter, shimmer, noise-to-harmonics ratio, and features derived from nonlinear analysis are considered, alongside variables like status, indicating the presence of neurological disorders, and class for classification purposes. Together, these attributes provide a detailed representation of voice signals, offering valuable insights into both neurological and voice disorders for research purposes. The dataset exhibits promising potential for applications in medical diagnostics and voice analysis. In the pursuit of accurate disease detection, various machine learning methodologies are employed, including Support Vector Machines (SVM), Random Forest (RF), Decision Tree (DT), Neural Networks (NN), and stateof-the-art Convolutional Neural Networks (CNNs). The incorporation of CNNs is pivotal, signifying a significant leap in accuracy of 100% for disease detection. The results showcase a model adept at discerning subtle changes associated with Parkinson's disease, with SVM achieving 96%, Decision Tree demonstrating a perfect 100%, Neural Network attaining 98%, and Random Forest showcasing an accuracy of 99%. This innovative approach not only transforms early Parkinson's disease identification through voice analysis, setting a precision benchmark, but also underscores the transformative potential of cutting-edge technologies in healthcare practices. The study positions the model as a reliable diagnostic tool, capable of advancing medical diagnostics through the seamless integration of biomedical research and machine learning, contributing to the broader field of neurodegenerative disease diagnostics.
• Zukunftsbibliotheken-SH: Gemeinsam für nachhaltige Entwicklung. 112. BiblioCon, Hamburg. Brümmer, Kathrin; Reichhardt, Tjorven (2024).

  Die Zukunftsbibliotheken-SH sind ein offener und wachsender Kreis von derzeit über 50 Öffentlichen Bibliotheken in Städten und Gemeinden von Schleswig-Holstein, die sich gemeinsam für eine gute Zukunft engagieren. Bei den 17 Ziele der Agenda 2030 erkennen wir vielfältige Mitgestaltungsmöglichkeiten im sozialen, ökologischen und gesellschaftlichen Bereich. Am Runden Tisch Grüne Bibliotheken planen und entwickeln wir Ideen, um uns aktiv an einer nachhaltigen Entwicklung zu beteiligen: beim Umgang mit Ressourcen, in der Bildungsarbeit, als öffentliche Räume der Begegnung, der kulturellen Teilhabe und Informationsvermittlung. Wir gestalten unsere Arbeit für und mit Menschen aller Generationen. Nachhaltige Entwicklung ist ein Prozess mit vielen Facetten. Es gibt lokale, regionale und globale Aspekte, die bei den verschiedenen Aktivitäten mit bedacht werden. Bei Ausstellungen, Workshops und Treffpunkten zu den deutschen Aktionstagen Nachhaltigkeit wie auch durch landesweite Projekte wie die glqqMobile Saatgutbibliothekgrqq, glqqErzählwegegrqq, glqqPicknick im Labyrinthgrqq, glqqMit Worten wachsengrqq oder textquotedblWir teilen Geschichtentextquotedbl ergeben sich vielfältige Mitgestaltungsmöglichkeiten an den einzelnen Orten. Im Blog der Website zukuntsbibliotheken-sh.de wird laufend über aktuelle Vorhaben und Praxismaterialien berichtet. Mit Zukunftsbibliotheken-sh ist keine spezielle Zertifizierung verbunden. Vielmehr geht es zunächst um eine Ermutigung zum Anfangen und Weitermachen: mit Projekten, mit Kooperationen zu ökologisch oder sozial engagierten Bildungspartnern, mit einem Umdenken bei der täglichen Arbeit. Gemeinsam stärken wir uns in der Qualitätsentwicklung durch Fortbildungen, Austausch und Beratung. Zur weiteren Vertiefung stehen den Bibliotheken z.B. die Möglichkeiten einer NUN-Zertifizierung, einer Klima-Bilanz oder einer Gemeinwohl-Bilanizierung offen.
• Platform Labour Unrest in a Global Perspective: How, Where and Why Do Platform Workers Protest?. Umney, Charles; Stuart, Mark; Bessa, Ioulia; Joyce, Simon; Neumann, Denis; Trappmann, Vera (2024). 38(1) 3–26.

  Labour unrest by platform workers is a growing global phenomenon, but several questions require deeper understanding. What motivates platform labour unrest? Which actors and strategies are involved? How does this vary across regions? Systematic answers are hindered by the lack of large datasets. Uniquely, this article analyses a global dataset comprising 1271 instances of platform labour unrest. It reveals two main dimensions of platform labour struggle: those defending or extending protective regulatory institutions (regulatory protests); and those seeking a larger share of value created (distributive protests). The former more often involve mainstream unions and methods like legal challenges. The latter more often involve grassroots organisation, and the collective withdrawal of labour and demonstrations. Theoretically, the article elaborates on Silver’s distinction between Marx-type and Polanyi-type labour unrest to explain and contextualise these findings. These patterns reveal variation within the growing wave of platform labour unrest that have not yet been systematically examined.
• 5G Technology: An Assessment of the Opportunities and Challenges in an Emerging Nigerian Society. Pahalson C. A. D, Davou Dung Gyang; Zungkat, Biya Alfred (2024).
• Comments on Monoids Induced by NFAs. Technical Report (2301), Holzer, Markus (2023).

  We summarize known results on the transformation monoid of nondeterministic finite automata (NFAs) from semigroup theory. In particular, we list what is known from the literature on the size of monoids induced by NFAs and their (minimal) number of generators—a comprehensive list of these generators is given in the Appendix. It is shown that any language accepted by an n-state NFA has a syntactic monoid of size at most 2n . This bound is reachable by the generators of the semigroup Bn of n×n Boolean matrices with the usual matrix multiplication except that we assume 1 + 1 = 1. The number of these generators grows exponentially in n. This is a significant difference to the deterministic case, where three generators suffice to generate all elements of Tn. Moreover, we prove a lower bound for the NFA-to-DFA conversion using Lambert’s W function.
• Machine Learning in Early Genetic Detection of Multiple Sclerosis Disease: A Survey. Ali, Nehal M.; Shaheen, Mohamed; Mabrouk, Mai S.; AboRezka, Mohamed A. (2020). 412–415.
• Marx und die Roboter. Vernetzte Produktion, Künstliche Intelligenz und lebendige Arbeit Butollo, Florian; Nuss, Sabine (2019). Dietz Berlin.

  Roboter, Künstliche Intelligenz und digitale Vernetzung trieben die Automatisierung der Produktion voran. Die lebendige Arbeit werde verschwinden, der Mensch endgültig ersetzbar, warnten die einen aufgeregt. Die anderen würden Wachstumspotenziale, Standortvorteile – oder sogar neue Chancen zur Überwindung des Kapitalismus sehen. Karl Marx sei Zeit seines Lebens fasziniert von den Potenzialen der Technik gewesen, Produktivkraft sei der Begriff, den er dafür prägte. Wie könne heute eine an Marx orientierte Analyse den technologischen Wandel erklären? Was sei das Neue, wo trete nur das Alte in anderer Form auf die Bühne? Brauche die Kritik des Kapitalismus neue Begriffe? In diesem Buch ertönt eine Vielzahl an Fragen und Antworten.
• On power BSD test of integrated circuits. Ostermann, Timm ijdms (ed.) (2017). (Vol. 10) 1.
• INSIGHT-DRIVEN BUSINESS RULES FOR OPERATIONAL KNOWLEDGE. Kaula, Rajeev (R. Kaula, ed.) (2017). 10(1) 1.
• On power BSD test of integrated circuits. Ostermann, Timm (2017). 412–415.
• MAGNETIZED PLASMA WITH FERROMAGNETIC GRAINS AS A VIABLE NEGATIVE REFRACTIVE INDEX MEDIUM. Technical Report (4), Mesfin, Belayneh (2015).

  The propagation of electromagnetic waves in a cold magnetized plasma with ferromagnetic grains (MPFG) in the high frequency domain is studied theoretically. The dispersion of MPFG which is controlled by the simultaneous characterization of the permittivity and permeability tensors. is investigated theoretically and numerically near the resonance frequency. It is found that MPFG becomes transparent for the waves that cannot propagate in conventional magnetized electron-ion plasma. The refractive index of the waves propagating parallel to the applied magnetic field is found to be negative for the extraordinary wave in certain frequency domain. The results obtained show that in a narrow band of the super-high-frequency range near the electron cyclotron frequency, MPFG possess all the known characteristics of negative refractive index media, which would make it as a viable alternative medium to demonstrate the known and predicted peculiar properties of media having negative index of refraction.
• Enhancing Network Security and Performance Using Optimized ACLS Tomar1, Kuldeep; and S.S Tyagi2 (2014). (Vol. 14)
• Cloud Computing Technology for Egovernment Architecture. Hashemi, Sajjad (2013). 13(06)
• FACE RECOGNITION USING DIFFERENT LOCAL FEATURES WITH DIFFERENT DISTANCE TECHNIQUES. Rao, M.Koteswara; Swamy, K.Veera; K.Anithasheela; Mohan, B.Chandra (2012). 2(1) 67–74.

  A face recognition system using different local features with different distance measures is proposed in this paper. Proposed method is fast and gives accurate detection. Feature vector is based on Eigen values, Eigen vectors, and diagonal vectors of sub images. Images are partitioned into sub images to detect local features. Sub partitions are rearranged into vertically and horizontally matrices. Eigen values, Eigenvector and diagonal vectors are computed for these matrices. Global feature vector is generated for face recognition. Experiments are performed on benchmark face YALE database. Results indicate that the proposed method gives better recognition performance in terms of average recognized rate and retrieval time compared to the existing methods.
• BIOMETRIC APPLICATION OF INTELLIGENT AGENTS IN FAKE DOCUMENT DETECTION OF JOB APPLICANTS. Bogle, Salathiel; Sankaranarayanan, Suresh (2012). 2(1) 75–94.

  The Job selection process in today’s globally competitive economy can be a daunting task for prospective employees no matter their experience level. Although many years of research has been devoted to job search and application resulting in good integration with information technology including the internet and intelligent agent-based architectures, there are still many areas that need to be enhanced. Two such areas include the quality of jobs associated with applicants in the job search by profiling the needs of employers against the needs of prospective employees and the security and verifications schemes integrated to reduce the instances of fraud and identity theft. The integration of mobile, intelligent agent, and cryptography technologies provide benefits such as improved accessibility wirelessly, intelligent dynamic profiling, and increased security. With this in mind we propose the intelligent mobile agents instead of human agents to perform the Job search using fuzzy preferences which is been published elsewhere and application operations incorporating the use of agents with a trust authority to establish employer trust and validate applicant identity and accuracy. Our proposed system incorporates design methodologies to use JADELEAP and Android to provide a robust, secure, user friendly solution.
• MODEL-DRIVEN SECURITY ASSESSMENT AND VERIFICATION FOR BUSINESS SERVICES. Technical Report (2), Thirumaran.M1; Dhavachelvan.P2; Abarna.S3; K, Thanigaivel. (2002).

  Information security covers many areas within an enterprise. Each area has security vulnerabilities and, hopefully, some corresponding countermeasures that raise the security level and provide better protection. The fundamental concepts in information security are the security model, which outlines how security is to be implemented. A security policy outlines how data is accessed, what level of security is required, and what actions should be taken when these requirements are not met. A security model is a statement that outlines the requirements necessary to properly support and implement a certain security policy. An important concept in the design and analysis of secure systems is the security model, because it incorporates the security policy that should be enforced in the system. A model is a symbolic representation of a policy. It maps the desires of the policy makers into a set of rules that are to be followed by a computer system. In the paper we propose a model driven security assessment and verification for business service. The Security Assessment and Verification verifies whether the Application and Services are secure based on the Service Level Agreement and generates the report on the level of security features. It is designed to help business owners, operators and staff to assess the security of their business. It covers potential areas of vulnerability, and provides suggestions for adapting your security to reduce the risk of crime against your business. A security policy states that no one from a lower security level should be able to view or modify information at a higher security level, the supporting security model will outline the necessary logic and rules that need to be implemented to ensure that under no circumstances can a lower-level subject access a higher-level object in an unauthorized manner. The security policy is an abstract term that represents the objectives and goals a system must meet and accomplish to be deemed secure and acceptable.
• Working with the European Works Council. Training Materials for EWC representatives. Stoop, Sjef (1999).

  This workbook on European Works Councils (EWCs) is designed as a training tool for people with some experience with EWCs, so it does not include the basics of the EWC such as the Directive or a checklist for agreements. It is also aimed at trainers and coordinators of EWCs, so outlines of training activities are included throughout the text. These are not comprehensive activity sheets. Trainers will need to adjust the material to the specific kind of training course: international or national, for one EWC or for reps from different EWCs, etc.
• DNA damage induced by bleomycin, neocarzinostatin, and melphalan in a precisely positioned nucleosome. Asymmetry in protection at the periphery of nucleosome-bound DNA. Smith, B L; Bauer, G B; Povirk, L F (1994). 269 30587–30594.
• Trade-Offs in Life-History Evolution. Stearns, S. C. (1989). 3(3) 259–268.

  Trade-offs represent the costs paid in the currency of fitness when a beneficial change in one trait is linked to a detrimental change in another. If there were no trade-offs, then selection would drive all traits correlated with fitness to limits imposed by history and design. ow ever, we find that many life-history traits are maintained well within those limits. Therefore, trade-offs must exist. Trade-offs have played a central role in the development of life-history theory, from Gadgil & Bossert (1970), Charnov & Krebs (1973), Schaffer (1972, 1974a, b) and Bell (1980) on to the present. They have been measured through field obser- vations (e.g. Clutton-Brock, Guinness & Albon, 1982, 1983),through experimental manipulations in laboratory (e.g. Partridge & Farquhar, 1981) and field (e.g. Askenmo, 1979), through phenotypic correlations in the laboratory (e.g. Bell, 1984a, b) and through genetic correlations (e.g. Rose & Charlesworth, 1981a, b), to mention only a few of the more prominent studies. They have been reviewed by Stearns (1976, 1977), Bell (1980), Charlesworth (1980), Warner (1984), Reznick (1985),Partridge & Harvey (1985, 1988) and most thoroughly by Bell & Koufopanou (1986).In addi- tion, the methods used to measure trade-offs have been the subject of criticism (Tuomi, Hakala & Haukioja, 1983; Partridge, 1987) and controversy (Reznick, Perry & Travis, 1986; Bell, 1986)
• Significance Tests Which May be Applied to Samples from Any Populations. Pitman, E. J. G. (1937). 4(1) 119–130.

  THE object of this paper is to show how we can devise valid tests of significance which involve no assumptions about the forms of the populations sampled. It is also shown that precise fiducial limits can be determined for the difference of means of populations of the same form, no matter what the form of the populations may be. While only one test is discussed in this paper, the principle is applicable to all tests. The main idea is not new, it seems to be implicit in all Fisher's writings; * but perhaps the approach to the subject, frankly starting from the sample and working towards the population instead of the reverse, may be a bit of a novelty.